Targeting TGF-beta for treatment of osteogenesis imperfecta

Song, IW; Nagamani, SC; Nguyen, D; Grafe, I; Sutton, VR; Gannon, FH; Munivez, E; Jiang, MM; Tran, A; Wallace, M; Esposito, P; Musaad, S; Strudthoff, E; McGuire, S; Thornton, M; Shenava, V; Rosenfeld, S; Huang, SX; Shypailo, R; Orwoll, E; Lee, B

Lee, B (通讯作者)，One Baylor Plaza, Houston, TX 77030 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2022; 132 (7):

Abstract

BACKGROUND. Currently, there is no disease-specific therapy for osteogenesis imperfecta (OI). Preclinical studies demonstrate that excessive TGF-beta ......

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