OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance

Yang, YF; Li, XR; Luan, HH; Zhang, BC; Zhang, KS; Nam, JH; Li, ZY; Fu, MN; Munk, A; Zhang, DY; Wang, SM; Liu, YY; Albuquerque, JP; Ong, QX; Li, R; Wang, Q; Robert, ME; Perry, RJ; Chung, DJ; Shulman, GI; Yang, XY

Yang, XY (corresponding author), Yale Univ, Dept Comparat Med, Program Integrat Cell Signaling & Neurobiol Metab, Sch Med, New Haven, CT 06520 USA.; Yang, XY (corresponding author), Yale Univ, Dept Cellular & Mol Physiol, Sch Med, New Haven, CT 06520 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (28): 16616

Abstract

Enhanced inflammation is believed to contribute to overnutrition-induced metabolic disturbance. Nutrient flux has also been shown to be essential for ......

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