MYCN mRNA degradation and cancer suppression by a selective small-molecule inhibitor in MYCN-amplified neuroblastoma

Liu, T; Gu, LB; Wu, ZZ; Albadari, N; Li, W; Zhou, MX

Zhou, MX (通讯作者)，Emory Univ, Sch Med, Dept Pediat, Atlanta, GA 30307 USA.;Zhou, MX (通讯作者)，Emory Univ, Aflac Canc & Blood Disorders Ctr, Sch Med, Atlanta, GA 30307 USA.

FRONTIERS IN ONCOLOGY, 2022; 12 ():

Abstract

Amplification of the MYCN gene leads to its overexpression at both the mRNA and protein levels. Overexpression of MYCN mRNA may also have an important......

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