Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth

Maresca, L; Crivaro, E; Migliorini, F; Anichini, G; Giammona, A; Pepe, S; Poggialini, F; Vagaggini, C; Giannini, G; Sestini, S; Borognoni, L; Lapucci, A; Dreassi, E; Taddei, M; Manetti, F; Petricci, E; Stecca, B

Manetti, F; Petricci, E (通讯作者)，Univ Siena, Dept Biotechnol Chem & Pharm, Siena, Italy.;Stecca, B (通讯作者)，Inst Canc Res & Prevent ISPRO, Core Res Lab, Viale Pieraccini 6, I-50139 Florence, Italy.

PHARMACOLOGICAL RESEARCH, 2023; 195 ():

Abstract

Aberrant activation of Hedgehog (HH) signaling in cancer is the result of genetic alterations of upstream pathway components (canonical) or other onco......

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