4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects

Liao, ST; Han, C; Xu, DQ; Fu, XW; Wang, JS; Kong, LY

Kong, LY (reprint author), China Pharmaceut Univ, Jiangsu Key Lab Bioact Nat Prod Res, Sch Tradit Chinese Pharm, 24 Tong Jia Xiang, Nanjing 210009, Jiangsu, Peoples R China.; Wang, JS (reprint author), China Pharmaceut Univ, State Key Lab Nat Med, Sch Tra

NATURE COMMUNICATIONS, 2019; 10 ():

Abstract

Activated macrophages switch from oxidative phosphorylation to aerobic glycolysis, similar to the Warburg effect, presenting a potential therapeutic t......

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