Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy

Sharma, NS; Gupta, VK; Garrido, VT; Hadad, R; Durden, BC; Kesh, K; Giri, B; Ferrantella, A; Dudeja, V; Saluja, A; Banerjee, S

Banerjee, S (corresponding author), Univ Miami, Dept Surg, Biomed Res Bldg,Rm 508,1551 Northwest 10th Ave, Miami, FL 33136 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2020; 130 (1): 451

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is considered to be a highly immunosuppressive and heterogenous neoplasm. Despite improved knowledge regarding......

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