PFKFB3 Inhibition Impairs Erlotinib-Induced Autophagy in NSCLCs

Lypova, N; Dougherty, SM; Lanceta, L; Chesney, J; Imbert-Fernandez, Y

Chesney, J; Imbert-Fernandez, Y (corresponding author), Univ Louisville, Sch Med, Dept Med, Louisville, KY 40202 USA.; Chesney, J; Imbert-Fernandez, Y (corresponding author), Univ Louisville, James Graham Brown Canc Ctr, Sch Med, Louisville, KY 40202 USA.

CELLS, 2021; 10 (7):

Abstract

Tyrosine kinase inhibitors (TKIs) targeting the kinase domain of the epidermal growth factor receptor (EGFR), such as erlotinib, have dramatically imp......

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