MD2 contributes to the pathogenesis of perioperative neurocognitive disorder via the regulation of alpha 5GABA(A) receptors in aged mice

Zuo, WQ; Zhao, JS; Zhang, JM; Fang, ZP; Deng, J; Fan, Z; Guo, YR; Han, J; Hou, WG; Dong, HL; Xu, FF; Xiong, LZ

Xu, FF; Xiong, LZ (corresponding author), Air Force Med Univ, Xijing Hosp, Dept Anesthesiol & Perioperat Med, Xian 710032, Peoples R China.; Xiong, LZ (corresponding author), Tongji Univ, Dept Anesthesiol & Perioperat Med, Shanghai Peoples Hosp 4, Sch Med,Translat Res Inst Brain & Brain Intellige, Shanghai 200434, Peoples R China.

JOURNAL OF NEUROINFLAMMATION, 2021; 18 (1):

Abstract

Background: Perioperative neurocognitive disorder (PND) is a long-term postoperative complication in elderly surgical patients. The underlying mechani......

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