Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis

Pai, CH; Lin, SR; Liu, CH; Pan, SY; Hsu, H; Chen, YT; Yen, CT; Yu, IS; Wu, HL; Lin, SL; Lin, SW

Lin, SW (corresponding author), Natl Taiwan Univ, Dept Clin Lab Sci & Med Biotechnol, Coll Med, Taipei 100, Taiwan.; Lin, SL (corresponding author), Natl Taiwan Univ, Grad Inst Physiol, Coll Med, Taipei 100, Taiwan.; Lin, SL (corresponding author), Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Coll Med, Taipei, Taiwan.; Lin, SL (corresponding author), Natl Taiwan Univ Hosp, Dept Integrated Diagnost & Therapeut, Taipei, Taiwan.; Lin, SL (corresponding author), Natl Taiwan Univ, Res Ctr Dev Biol & Regenerat Med, Taipei, Taiwan.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

The role of fibroblasts in tissue fibrosis has been extensively studied. Activated fibroblasts, namely myofibroblasts, produce pathological extracellu......

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