JAHA:肥胖和臭氧对PM2.5与心血管死亡风险相关性的影响

2018-06-01 MedSci MedSci原创

心血管疾病和卒中是全球最大的健康杀手之一,既往研究揭示了短期或长期的大气颗粒物污染(PM2.5)的暴露会增加心血管疾病和卒中的死亡风险。本次横断面研究结合分析了美国国家数据库中的心血管疾病和卒中死亡率、高血压和肥胖的发病率,并分析了其与PM2.5和臭氧水平的关系。分析结果显示,心血管疾病死亡风险(β=15.4, P<0.001)和卒中死亡风险(β=2.7, P<0.001)与PM2.5

血管疾病和卒中是全球最大的健康杀手之一,既往研究揭示了短期或长期的大气颗粒物污染(PM2.5)的暴露会增加心血管疾病和卒中的死亡风险。

本次横断面研究结合分析了美国国家数据库中的心血管疾病和卒中死亡率、高血压和肥胖的发病率,并分析了其与PM2.5和臭氧水平的关系。分析结果显示,心血管疾病死亡风险(β=15.4, P<0.001)和卒中死亡风险(β=2.7, P<0.001)与PM2.5呈强相关性,而臭氧仅与心血管疾病死亡风险相关联(β=1372.1, P<0.001),且这些关联不与贫富程度、种族和受教育程度相关。PM2.5和臭氧均是独立的危险因子。此外,PM2.5对心血管疾病死亡和卒中死亡的影响很大程度上依赖于肥胖,高血压也有部分参与。

研究结果显示,心血管疾病死亡风险与PM2.5和臭氧的暴露呈强相关,卒中的死亡风险与PM2.5的暴露相关。且PM2.5对心血管疾病死亡的影响在肥胖人群中更为显着。

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    2018-06-03 zhaohui6731
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    2018-06-03 xuqianhua
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    2018-06-02 blueisback

    我国夏季臭氧污染也要重视

    0

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