J Rheumatol:系统性红斑狼疮卒中后的死亡率和功能障碍

2017-10-25 xiangting MedSci原创

与非SLE患者相比,SLE患者第一个月后缺血性卒中的死亡率升高,3个月时的功能更差。

这篇文章旨在探讨系统性红斑狼疮(SLE)卒中后的死亡率及功能障碍。

使用瑞典全国登记确定了423例SLE患者和1652例无SLE首次出现缺血或出血卒中的患者(1998 - 2013年),并随访至全因死亡或1年。计算缺血性/出血性卒中后的死亡HR和缺血性卒中3个月后功能障碍(根据行走、如厕或穿衣)的风险比。

卒中后一年,22%SLE患者vs.16%非SLE患者死亡。缺血性卒中后,SLE患者死亡风险升高(HR 1.85,95%CI 1.39-2.45),其在控制SLE相关并发症后降低(HR 1.41,95%CI 1.04-1.91)。SLE3个月功能障碍增加了近2倍(风险比为1.73,95%CI为1.16-2.57)。出血性卒中后SLE患者死亡HR为2.30(95%CI 1.38-3.82),即使在第一个月即有所升高。

与非SLE患者相比,SLE患者第一个月后缺血性卒中的死亡率升高,3个月时的功能更差。即使在第1个月,SLE与出血性卒中后的全因死亡率相关。需要将重点转移到患者功能和预防出血性卒中上来。 

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    2017-10-27 zhouqu_8
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    2017-10-25 中医痴

    不错的.学习了.谢谢分享!

    0

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