JACC Heart Fail:2型糖尿病患者需警惕更高的心脏病死亡风险!

2017-11-18 佚名 medicalxpress

一项新的研究发现,预先存在2型糖尿病的心力衰竭患者的住院率和死亡率较高,但保持血糖平衡可以帮助将这种风险降低到无糖尿病心力衰竭患者的风险。

一项新的研究发现,预先存在2型糖尿病的心力衰竭患者的住院率和死亡率较高,但保持血糖平衡可以帮助将这种风险降低到无糖尿病心力衰竭患者的风险。

这项由基尔大学研究人员克莱尔·劳森(Claire Lawson)领导的研究,与莱斯特大学(University of Leicester)合作,强调了2型糖尿病与心力衰竭之间复杂的相互作用。

这是新诊断的心力衰竭患者的一般人群中第一个也是最大的研究,显示了与2型糖尿病和药物治疗相关的风险。该研究调查了英国49,000名心脏病患者,并调查了血糖控制水平和药物治疗强度似乎给糖尿病患者带来更多风险。

在为期12年的研究中,患有糖尿病的心力衰竭患者在入院前六个月或者一年之后,跟踪了死亡之前糖化血红蛋白水平(体内红细胞携带的葡萄糖量)和药物治疗信息,比较有和没有2型糖尿病的心力衰竭患者的结果。

如果2型糖尿病患者的糖化血红蛋白水平大于80mmol或低于37mmol,那么他们的住院和死亡风险更高。但是,保持非常好的稳定的糖化血红蛋白水平的患者没有比非糖尿病患者更高的入院或死亡风险。

基尔大学成人护理讲师克莱尔·劳森说:“新的心力衰竭患者预先存在的2型糖尿病使死亡风险增加了50%,鉴于新诊断的心力衰竭患者基线死亡风险已经很高,有临床意义。

“我们的研究结果显示,2型糖尿病患者和全因住院和死亡患者的糖化血红蛋白水平之间的关系是U型的,这意味着高水平和低水平的患者显著增加了在六个月内入院的风险,糖化血红蛋白不稳定性在6个月或12个月内变化1%,也与入院或死亡风险增加有关。

研究人员认为,这些研究结果强调了保持血糖水平在健康范围内的重要性,以减少这种并发症,糖尿病患者的糖化血红蛋白目标应根据其心力衰竭症状的进展个性化控制。

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    2017-11-20 zhaojie88
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    2017-11-20 slcumt
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    2017-11-18 changjiu

    学习一下谢谢

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