J Pediatr:胃残留抽吸对早产极低出生体重儿胃肠功能、肠道炎症、胃肠粘膜出血的影响

2020-11-09 MedSci原创 MedSci原创

本研究旨在测定胃残留抽吸及评价对早产极低出生体重儿胃肠功能、肠道炎症、胃肠粘膜出血的影响。

本研究旨在测定胃残留抽吸及评价对早产极低出生体重儿胃肠功能、肠道炎症、胃肠粘膜出血的影响。
该单中心随机试验比较了143名孕期≤32周、出生体重≤1250g的婴儿出生后6周的胃残留物与喂养前胃残留物。在出生后14~21天采集血清中胃泌素和运动素水平。在3周和6周龄时采集粪便,分析钙蛋白和S100A12水平。所有粪便都进行了6周的隐血检测。
 
结果显示,组间胃泌素(P = .999)和motilin(P = .694)的平均值相似,转化钙蛋白(P = .580)和S100A12(P = .212)的校正平均值没有统计学意义。从第3周到第6周,钙蛋白(P = .003)和S100A12(P = .002)均增加。各组间隐血阳性的粪便平均百分比(P = .888)相似。
综上所述,该研究结果表明,胃肠功能、肠道炎症和胃肠粘膜出血,无论是否消除抽吸和评估胃残留物都是相似的,这表明在每次进食前常规评估胃残留物可能是不必要的。
 
原始出处:
 
Leslie A Parker, Michael Weaver, et al., Effect of Aspiration and Evaluation of Gastric Residuals on Intestinal Inflammation, Bleeding, and Gastrointestinal Peptide Level. J Pediatr. 2020 Feb;217:165-171.e2. doi: 10.1016/j.jpeds.2019.10.036.  Epub 2019 Nov 19.

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    2022-01-10 ms1000001992064009

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    2021-03-23 feather89
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    2020-11-18 guoyibin
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