Am J Clin Nut:空腹血糖和胰岛素含量可以作为减肥成功与否的生物标志物

2017-07-08 小小羊 来宝网

哥本哈根大学营养与运动系的研究人员在今天出版的美国临床营养学杂志(AJCN)上发表了他们关于减肥生物标志物研究结果。通过研究“预处理空腹血糖或胰岛素、调整饮食和实现体重减轻:3项随机临床试验”发现,空腹血糖或胰岛素含量可以用于改善饮食并预测体重减轻,尤其是对于患有糖尿病的人来说。



正在减肥!现在可以通过空腹血糖含量决定你的食谱了】哥本哈根大学营养与运动系的研究人员在今天出版的美国临床营养学杂志(AJCN)上发表了他们关于减肥生物标志物研究结果。通过研究“预处理空腹血糖或胰岛素、调整饮食和实现体重减轻:3项随机临床试验”发现,空腹血糖或胰岛素含量可以用于改善饮食并预测体重减轻,尤其是对于患有糖尿病的人来说。

该研究分析了三种临床饮食试验的数据,这些试验总共观察了1200多个体的 - 饮食,肥胖和基因(Diogenes);OPUS超市干预(SHOPUS);营养物 - 基因在人类肥胖中的相互作用(NUGENOB)。研究结果表明,对于大多数患有早期糖尿病的人来说,应该推荐富含有蔬菜水果和全脂的饮食以减肥,这有可能改善糖尿病标志物。对于2-型糖尿病患者,分析发现,来自植物的富含健康脂肪的饮食对于实现减肥是有效的。 这些饮食不考虑热量限制而发挥作用。

哥本哈根大学营养与运动系主任Arne Astrup博士说:“认识到空腹血糖的关键性生物标志物的作用能够对以前研究数据进行新的解释,这可能会引出个性化营养领域的突破”。“这个概念的美丽在于它的简单性,在我们研究其他生物标志物的同时,通过使用这两种简单的生物标志物,我们可以为病人做更多的工作,我们将继续参与并支持研究探索新的生物标志物,如肠道微生物群和基因组学方法,这些方法可以提供更多的见解,并帮助我们更有效地为特定个体定制正确的饮食。

据AJCN报道,最新的研究结果获得了国际支持,并得到了科罗拉多大学,塔夫茨大学和生物技术研究中心(CIBER OBN)的研究人员的进一步分析。 并于2017年6月11日在美国糖尿病协会第77届科学会议上提出,额外的研究包括对患者的Prevencion Dieta Mediterranea(PREDIMED研究)、Low-CHO饮食肥胖的随机试验(CHO研究)进行测试,以及生活学习的健康体重的研究。 不同的研究(总共六个)采用各种营养策略,包括热量限制和随意饮食,改变碳水化合物和脂肪的贡献,增加纤维摄入量。

该研究的灵感来自于Gelesis100早期试验的一个发现,Gelesis100是一种新型水凝胶,其在糖尿病前期有明显的减轻体重的作用。最新的发现,如在AJCN发表的文章,表明基于个人生物标志物的个性化营养方法能提高减轻并维持体重的成功率。哥本哈根大学将继续与研究作者和其他专家合作推进这项研究,并帮助世界各地正在减肥的人们寻找解决方案。

原始出处:

Mads F Hjorth et al, Pretreatment fasting plasma glucose and insulin modify dietary weight loss success: results from 3 randomized clinical trials, The American Journal of Clinical Nutrition (2017). DOI: 10.3945/ajcn.117.155200.

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    2018-03-18 baoya
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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Jul 08 22:25:57 CST 2017, time=2017-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220057, encodeId=515422005e3e, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Jul 08 20:25:26 CST 2017, time=2017-07-08, status=1, ipAttribution=)]
    2017-07-09 龙胆草

    学习谢谢分享

    0

  7. 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createdName=baoya, createdTime=Sun Mar 18 13:43:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304958, encodeId=6de11304958d1, content=<a href='/topic/show?id=1970e539018' target=_blank style='color:#2F92EE;'>#空腹血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75390, encryptionId=1970e539018, topicName=空腹血糖)], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160723/IMG57937A3BB59F33185.jpg, createdBy=7642322, createdName=手留余香, createdTime=Mon Jul 10 10:43:00 CST 2017, time=2017-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560625, encodeId=8e40156062507, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Jul 08 22:25:57 CST 2017, time=2017-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220057, encodeId=515422005e3e, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Jul 08 20:25:26 CST 2017, time=2017-07-08, status=1, ipAttribution=)]
    2017-07-09 惠映实验室

    学习了,谢谢

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Jul 08 22:25:57 CST 2017, time=2017-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220057, encodeId=515422005e3e, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Jul 08 20:25:26 CST 2017, time=2017-07-08, status=1, ipAttribution=)]
    2017-07-09 189****1577

    值得推荐一下

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Jul 08 22:25:57 CST 2017, time=2017-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220057, encodeId=515422005e3e, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Jul 08 20:25:26 CST 2017, time=2017-07-08, status=1, ipAttribution=)]
    2017-07-08 有备才能无患

    该研究的灵感来自于Gelesis100早期试验的一个发现,Gelesis100是一种新型水凝胶,其在糖尿病前期有明显的减轻体重的作用。

    0

  10. 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    2017-07-08 1ddf0692m34(暂无匿称)

    学习了,涨知识

    0

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