JCLA:超敏前列腺特异性抗原水平作为机器人辅助根治性前列腺切除术后生化进展的预测指标?

2019-07-12 不详 网络

本研究目的是确定USPSA作为机器人辅助根治性前列腺切除术(RARP)后生化复发(BCR)预测器的有效性。本回顾性研究包括213例术后USPSA在0.01 - 0.2 ng/mL之间且随访至少2年的前列腺癌患者。我们建立了PSA≥0.2和≥0.5 ng/mL的BCR预测模型。 共有103名患者(48.3%)在中位随访13.3个月时出现BCR。更高的术后USPSA(比值比(或)= 4.73,P

本研究目的是确定USPSA作为机器人辅助根治性前列腺切除术(RARP)后生化复发(BCR)预测器的有效性。本回顾性研究包括213例术后USPSA0.01 - 0.2 ng/mL之间且随访至少2年的前列腺癌患者。我们建立了PSA0.2和≥0.5 ng/mLBCR预测模型。

共有103名患者(48.3%)在中位随访13.3个月时出现BCR。更高的术后USPSA(比值比()= 4.73,P < 0.01),两国积极手术边缘双方(= 1.32,P = 0.044),更高的平均PSA升高(= 1.67,P = 0.031), ISUP3年级组(= 1.48,P = 0.003),以及更短的间隔自RARP(= 0.58,P < 0.001)BCRPSA的独立预测指标≥0.2 ng / mL。术后USPSA较高(OR = 3.85, P < 0.01),双侧手术切缘阳性(OR = 1.34, P = 0.011) ISUP分级组≥3 (OR = 1.5, P = 0.002) RARP较短(OR = 0.61, P = 0.001)BCR的独立预测因子,PSA0.5 ng/mL。第一模型和第二模型曲线下面积分别为0.8650.834

RARP术后超敏PSABCR的一种有效的预后指标,可指导术后风险分层和术后随访计划。

原始出处:

Nikolaos Grivas , Daan de Bruin ,Ultrasensitive prostatespecific antigen level as a predictor of biochemical progression after robotassisted radical prostatectomy: Towards risk adapted followup

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  5. 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attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=13dc16973127, createdName=ms6279672939590805, createdTime=Sun Jul 14 05:28:00 CST 2019, time=2019-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586148, encodeId=81721586148d6, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Sun Jul 14 05:28:00 CST 2019, time=2019-07-14, status=1, ipAttribution=)]
  6. 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05:28:00 CST 2019, time=2019-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1513326, encodeId=84c515133262d, content=<a href='/topic/show?id=6a446120454' target=_blank style='color:#2F92EE;'>#机器人辅助#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61204, encryptionId=6a446120454, topicName=机器人辅助)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=324410545094, createdName=124987a0m69(暂无昵称), createdTime=Sun Jul 14 05:28:00 CST 2019, time=2019-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1583191, encodeId=a1611583191d3, content=<a href='/topic/show?id=f6e1611840d' target=_blank style='color:#2F92EE;'>#机器#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61184, encryptionId=f6e1611840d, topicName=机器)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=13dc16973127, createdName=ms6279672939590805, createdTime=Sun Jul 14 05:28:00 CST 2019, time=2019-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586148, encodeId=81721586148d6, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Sun Jul 14 05:28:00 CST 2019, time=2019-07-14, status=1, ipAttribution=)]
    2019-07-14 xue8602
  7. 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  8. 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