JAHA:妊娠期高血压患者子代出现心血管代谢异常的风险更高!

2018-01-08 MedSci MedSci原创

目前,对于妊娠期高血压(HDP)患者子代成年后的心血管代谢健康状况尚属未知。本研究目的旨在评估HDP患者子代成年后视网膜微血管和心脏的结构变化。本研究纳入了1006名孕期≥37周出生的子代,并在其成年期对视网膜微血管和心脏结构进行评估,评估时的平均年龄为40岁(34-49岁)。结果发现,与正常妊娠的子代相比,妊娠期高血压子代的收缩压更高(β=4.68, P<0.001),体重指数更高(β=1

目前,对于妊娠期高血压(HDP)患者子代成年后的心血管代谢健康状况尚属未知。本研究目的旨在评估HDP患者子代成年后视网膜微血管和心脏的结构变化。本研究纳入了1006名孕期≥37周出生的子代,并在其成年期对视网膜微血管和心脏结构进行评估,评估时的平均年龄为40岁(34-49岁)。结果发现,与正常妊娠的子代相比,妊娠期高血压子代的收缩压更高(β=4.68, P<0.001),体重指数更高(β=1.25, P=0.009),腰围也更大(β=0.25, P=0.042),而在空腹血糖、血脂、胰岛素和颈动脉内膜中层厚度无明显差异。经年龄和性别调整后,发现HDP子代的视网膜小动脉直径更小(β=-0.43, P=0.009),并且更长(β=32.5, P=0.023),长度/直径比值更大(β=2.32, P=0.006)。此外,HDP子代的左心房容积与体表面积比值更大(β=1.34, P=0.040)。研究结果显示,妊娠期高血压患者子代在成年后的视网膜血管和心脏结构均存在异常。原始出处:Robyn J et al.Cardiometabolic Health Among Adult Offsp

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    2018-10-26 楚钟
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    2018-01-26 一个字-牛

    学习了谢谢分享

    0

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    2018-01-10 zhaohui6731
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    2018-01-08 邓启付

    妊娠期高血压对子代心血管健康也有影响.学习了!

    0

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