Am J Cardiol:急性心肌梗死后远期死亡风险升高,年轻者也需警惕!

2016-07-29 MedSci MedSci原创

近日,来自新加坡国立大学的一项新的研究显示,急性心肌梗死的年轻患者远期死亡风险大大高于匹配年龄及性别的无急性心肌梗死的背景人群,该研究结果已发表于The American Journal of Cardiology。 但是,研究人员表示,与年老的心肌梗死患者相比,年轻患者的预后较好。 研究中,研究人员纳入分析了2000-2005年的15151名心肌梗死患者的数据,其中601名(6.8%

近日,来自新加坡国立大学的一项新的研究显示,急性心肌梗死的年轻患者远期死亡风险大大高于匹配年龄及性别的无急性心肌梗死的背景人群,该研究结果已发表于The American Journal of Cardiology。


但是,研究人员表示,与年老的心肌梗死患者相比,年轻患者的预后较好。

研究中,研究人员纳入分析了2000-2005年的15151名心肌梗死患者的数据,其中601名(6.8%为女性; 53.7%为中国人)患者年龄≤40岁,14550名(28.6% 为女性; 67.2% 为中国人)患者年龄>40岁。

中位随访时间为7.31年,在这期间共有7454名患者死亡。老年组患者的全因死亡率(50.7%)高于年轻组患者(12.8%; P <0.001)。34.5%的老年患者发生心血管疾病死亡,而年轻组仅为9.2%(P <0.001)。

将匹配年龄的背景人群(n = 3,771,700)除以急性心肌梗死幸存者得到的比例定为相对死亡率(RSR)。结果发现,第1年时,年轻组患者RSR为0.969 (95% CI, 0.95-0.98),年老组为0.804 (95% CI, 0.797-0.811)。年轻组患者5年RSRs 为0.942 (95% CI, 0.918-0.96),年老组为0.716 (95% CI, 0.707-0.726);而第9年时,年轻组患者的RSRs 为0.908 (95% CI, 0.878-0.938),年老组则为0.638 (95% CI, 0.62-0.654)。

与年老组患者相比,年轻组患者的长期死亡率低5倍,但是应避免吸烟,因为吸烟是导致患者死亡的重要危险因素。

既往一项研究曾表明,持续吸烟是导致早发性心肌梗死患者心脏疾病复发的最强预测因子。因此,在初级预防阶段应强调避免吸烟的重要性。

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    2016-10-09 1e0ece0dm09(暂无匿称)

    谢谢分享谢谢

    0

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    2016-09-25 1e10c84am36(暂无匿称)

    文章很好值得关注

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    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

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背景:既往研究显示心肌梗死后缺血性卒中的风险增加(IS),但是其长期的风险和是否与心脏损伤直接损伤相关尚不清楚。研究者假设如果有证据证明心肌损伤,急性冠脉综合征后IS的风险明显高于非心肌损伤者,心肌损伤如ST段抬高型心肌梗死(STEMI)和非ST段抬高型心肌梗死,表明心肌未损伤,如不稳定型心绞痛。方法和结果:纳入数据为2008和2011期间,利福尼亚非联邦急性护理医院急诊和住院部。使用适当的国际疾

JAHA:高水平的sIL-6R与STEMI患者未来心血管事件和死亡率相关

背景:ST段抬高型心肌梗死(STEMI)患者可溶性白细胞介素-6(IL-6)受体(sIL-6R)和糖蛋白130(sgp130)的报道较少,包括一小部分患者。本研究的目的是探讨急性期STEMI这些生物标志物水平与未来心血管事件可能存在的相关性。方法和结果:2007-2011期间,检测了989例STEMI患者循环中IL-6、sgp130、sIL-6R,和C-反应蛋白(CRP),并且在随访期间,记录心血

JACC:非心脏手术后出现围手术期心肌梗死的死亡率高

近期发表在Journal of the American College of Cardiology的研究称,非心脏手术后出现围手术期心肌梗死的患者有很高的死亡率,即使他们接受PCI治疗。佛蒙特大学医学中心的Harold L. Dauerman博士对1093例在克利夫兰诊所进行非心脏手术、术后7天内出现围手术期心肌梗死的患者数据进行了分析研究。随访3832人年。接受PCI的患者中有281名为ST段