Obesity:肥胖孕妈妈一定要控制好体重

2015-04-16 Mechront 译 MedSci原创

已有相当多的研究表明,孕妇肥胖会导致大于胎龄儿(LGA)和小于胎龄儿(SGA)的风险增加,导致后代肥胖风险增加。Catov JM等人进行了一项研究,想探究不同孕期体重增长(GWG)模式与LGA、SGA发生率间的联系,以及何种GWG模式可以减少或抵消此类风险。

已有相当多的研究表明,孕妇肥胖会导致大于胎龄儿(LGA)和小于胎龄儿(SGA)的风险增加,导致后代肥胖风险增加。Catov JM等人进行了一项研究,想探究不同孕期体重增长(GWG)模式与LGA、SGA发生率间的联系,以及何种GWG模式可以减少或抵消此类风险。


该研究共纳入651名超重/肥胖女性,根据该队列孕期体重变化情况归纳总结出GWG模式。通过多分类logistic回归模型分析GWG模式和胎儿以下出生体重结局的联系:小于胎龄儿(SGA:出生体重<10个百分位数)和大于胎龄儿(LGA:出生体重>90个百分位数)。

研究结果显示,整体队列中SGA的发生率高于LGA(14.9% vs. 7.8%)。根据孕妇体重增长情况共发现有4种GWG模式:体重增加持续偏多(29%)、早期体重增加合适,晚期则增加过多(33%)、整个孕期体重增加处于合适水平(18%)、整个孕期体重增加偏少(20%)。在整个孕期体重增加偏多的GWG模式组,其胎儿LGA的风险最高(OR 4.62 [1.53, 13.96])。早期体重控制合理而晚期体重增加偏多的孕妇其胎儿LGA发生率位居第二(OR 3.07 [1.01, 9.37])。只要在孕20周前,体重增加偏多的GWG模式,不管后面体重控制如何,均与LGA的发生密切相关,导致其发生风险增加。孕20周前体重增加偏少,而之后体重增加偏多或许可以减少SGA风险(0.55 [0.29, 1.07])。

研究结果表明,对于超重/肥胖孕妇,孕期体重增长模式多胎儿生长至关重要,或许可以作为胎儿生长异常的一种提示。

原始出处:


Catov JM, Abatemarco D, Althouse A, Davis EM, Hubel C. Patterns of gestational weight gain related to fetal growth among women with overweight and obesity. Obesity
(Silver Spring). 2015 .

本文系Medsci原创编译整理!转载需要先获得授权,并附原文链接。谢谢!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1932335, encodeId=45d419323359e, content=<a href='/topic/show?id=97cc452e63f' target=_blank style='color:#2F92EE;'>#孕妈妈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45276, encryptionId=97cc452e63f, topicName=孕妈妈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c737344, createdName=lg.zhao, createdTime=Mon Apr 20 14:12:00 CST 2015, time=2015-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22953, encodeId=792a2295385, content=母亲健康很重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=qingfengqishi5, createdTime=Fri May 08 15:31:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1910467, encodeId=c0c6191046e9d, content=<a href='/topic/show?id=faf7163606a' target=_blank style='color:#2F92EE;'>#SIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16360, encryptionId=faf7163606a, topicName=SIT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Thu Feb 25 02:12:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461729, encodeId=843e1461e295e, content=<a href='/topic/show?id=92c2132003b' target=_blank style='color:#2F92EE;'>#Obesity#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13200, encryptionId=92c2132003b, topicName=Obesity)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45616444603, createdName=lingaifan, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588177, encodeId=bd7915881e7dc, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=)]
    2015-04-20 lg.zhao
  2. [GetPortalCommentsPageByObjectIdResponse(id=1932335, encodeId=45d419323359e, content=<a href='/topic/show?id=97cc452e63f' target=_blank style='color:#2F92EE;'>#孕妈妈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45276, encryptionId=97cc452e63f, topicName=孕妈妈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c737344, createdName=lg.zhao, createdTime=Mon Apr 20 14:12:00 CST 2015, time=2015-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22953, encodeId=792a2295385, content=母亲健康很重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=qingfengqishi5, createdTime=Fri May 08 15:31:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1910467, encodeId=c0c6191046e9d, content=<a href='/topic/show?id=faf7163606a' target=_blank style='color:#2F92EE;'>#SIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16360, encryptionId=faf7163606a, topicName=SIT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Thu Feb 25 02:12:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461729, encodeId=843e1461e295e, content=<a href='/topic/show?id=92c2132003b' target=_blank style='color:#2F92EE;'>#Obesity#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13200, encryptionId=92c2132003b, topicName=Obesity)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45616444603, createdName=lingaifan, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588177, encodeId=bd7915881e7dc, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=)]
    2015-05-08 qingfengqishi5

    母亲健康很重要。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1932335, encodeId=45d419323359e, content=<a href='/topic/show?id=97cc452e63f' target=_blank style='color:#2F92EE;'>#孕妈妈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45276, encryptionId=97cc452e63f, topicName=孕妈妈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c737344, createdName=lg.zhao, createdTime=Mon Apr 20 14:12:00 CST 2015, time=2015-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22953, encodeId=792a2295385, content=母亲健康很重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=qingfengqishi5, createdTime=Fri May 08 15:31:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1910467, encodeId=c0c6191046e9d, content=<a href='/topic/show?id=faf7163606a' target=_blank style='color:#2F92EE;'>#SIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16360, encryptionId=faf7163606a, topicName=SIT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Thu Feb 25 02:12:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461729, encodeId=843e1461e295e, content=<a href='/topic/show?id=92c2132003b' target=_blank style='color:#2F92EE;'>#Obesity#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13200, encryptionId=92c2132003b, topicName=Obesity)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45616444603, createdName=lingaifan, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588177, encodeId=bd7915881e7dc, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=)]
    2016-02-25 智慧医人
  4. [GetPortalCommentsPageByObjectIdResponse(id=1932335, encodeId=45d419323359e, content=<a href='/topic/show?id=97cc452e63f' target=_blank style='color:#2F92EE;'>#孕妈妈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45276, encryptionId=97cc452e63f, topicName=孕妈妈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c737344, createdName=lg.zhao, createdTime=Mon Apr 20 14:12:00 CST 2015, time=2015-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22953, encodeId=792a2295385, content=母亲健康很重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=qingfengqishi5, createdTime=Fri May 08 15:31:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1910467, encodeId=c0c6191046e9d, content=<a href='/topic/show?id=faf7163606a' target=_blank style='color:#2F92EE;'>#SIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16360, encryptionId=faf7163606a, topicName=SIT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Thu Feb 25 02:12:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461729, encodeId=843e1461e295e, content=<a href='/topic/show?id=92c2132003b' target=_blank style='color:#2F92EE;'>#Obesity#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13200, encryptionId=92c2132003b, topicName=Obesity)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45616444603, createdName=lingaifan, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588177, encodeId=bd7915881e7dc, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=)]
    2015-04-17 lingaifan
  5. [GetPortalCommentsPageByObjectIdResponse(id=1932335, encodeId=45d419323359e, content=<a href='/topic/show?id=97cc452e63f' target=_blank style='color:#2F92EE;'>#孕妈妈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45276, encryptionId=97cc452e63f, topicName=孕妈妈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c737344, createdName=lg.zhao, createdTime=Mon Apr 20 14:12:00 CST 2015, time=2015-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22953, encodeId=792a2295385, content=母亲健康很重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=qingfengqishi5, createdTime=Fri May 08 15:31:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1910467, encodeId=c0c6191046e9d, content=<a href='/topic/show?id=faf7163606a' target=_blank style='color:#2F92EE;'>#SIT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16360, encryptionId=faf7163606a, topicName=SIT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Thu Feb 25 02:12:00 CST 2016, time=2016-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461729, encodeId=843e1461e295e, content=<a href='/topic/show?id=92c2132003b' target=_blank style='color:#2F92EE;'>#Obesity#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13200, encryptionId=92c2132003b, topicName=Obesity)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=45616444603, createdName=lingaifan, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588177, encodeId=bd7915881e7dc, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Fri Apr 17 15:12:00 CST 2015, time=2015-04-17, status=1, ipAttribution=)]
    2015-04-17 skhzy

相关资讯

Obesity:怀孕让肥胖女性更健康

众所周知,超重/肥胖人群的心血管疾病罹患风险会增加,但是这群人中,对于育龄期女性,怀孕这个特殊神圣的过程能否让其风险发生改变呢?Niemczyk NA等人在超重/肥胖的育龄期女性中进行了一项研究,以探究亚临床心血管疾病(CVD)与产次的关系。

Diabetes:GLP-1五肽小分子可抑制肥胖

目前,因肥胖而导致的糖尿病在全世界范围内越来越普遍流行。近日,美国科学家在国际学术期刊Diabetes在线发表了一项最新科研进展,他们发现来源于胰高血糖素样肽GLP-1氨基端的五肽能够促进基础能量消耗,促进饮食诱导的小鼠模型抵抗肥胖发生,并能改善代谢,具有重要开发价值。 研究人员发现的这种五肽小分子能够通过增加基础能量消耗、抑制肥胖过程的发展,改善饮食诱导的肥胖小鼠的胰岛素敏感性、糖尿病

同一团队连发两篇文章:谁控制着你的口腹之欲

肥胖是现代工业社会的一种流行病,随着人们饮食习惯和生活方式的改变,全球的肥胖发病率正在逐年攀升,已经成为了世界性的健康问题。大脑深处的下丘脑中聚集着上万个POMC神经元,它们是饱足感和饥饿感的控制中心,能根据机体信号对食欲和进食行为进行调节。科学家们一直希望能够通过操纵这些神经元来解决肥胖问题。密歇根大学的Malcolm Low博士和布宜诺斯艾利斯大学的Marcelo Rubinstein博士陆续

Nature:肥胖相关受体具有独特结构

发表在国际著名杂志Nature上的一篇研究论文中,来自日本理化研究所等处的研究人员通过利用名为SPring-8的同步加速器阐明了脂连素两种受体的结构,脂连素是一种和肥胖及糖尿病直接相关的蛋白质,研究人员希望本文研究可以为后期设计新型药物靶向作用AdipoR1和AdipoR2受体来降低和糖尿病相关的早期死亡率提供新的思路。 脂连素是一种由脂肪细胞分泌产生的激素蛋白,其被认为可以参与葡萄糖及脂肪

Diabetes Care:小心中央肥胖会带给你2型糖尿病的风险

目的:腹部肥胖是2型糖尿病(T2D)的主要危险因素。我们的目的是研究遗传易感性向心性肥胖之间的关联,通过腰围与臀围的比例(WHR)基因分和T2D风险进行评估。 研究设计和方法:目前的研究包括2591名2型糖尿病患者和3052名无2型糖尿病参与者,这些参与者均为欧洲血统来自于护士健康研究的(NHS)和卫生专业人员随访研究(HPFS)。使用基于14位点建立了WHR遗传得分估计遗传倾向向心性肥胖。

Scientific Reports:心血来潮的一次运动或许并不能让你更健康

肝脂质含量(肝内脂质,IHL)的增加会导致其代谢并发症风险增加。有研究表明,有规律的耐力训练可以减少代谢疾病风险,可以降低IHL水平。但是短期身体活动是否与耐力训练有类似效果还不知道。