BMJ:重新审视中国高龄老人血压与死亡风险

2018-06-06 zhangfan MedSci原创

研究发现,对于中国90岁以上高龄老年人群,其血压与死亡风险呈U相关。血压较高人群的心血管死亡风险增加,而较低人群的非心血管死亡风险增加,这一研究发现强调了在高龄老年人群中重新审视血压管理或制定具体的管理指南的重要性

近日研究人员就中国高龄老年人血压与3年内全死因及特异性死亡风险之间的关系进行了考察。

本次研究为2011-2014年间老年人群健康长寿调查研究的一部分,总计22个省,4658名高龄老年人参与,参与者平均年龄92.1岁。研究的主要终点是3年随访期间参与者全因死亡以及特异性死亡。

3年间总计1997人死亡,死亡率与收缩压、平均动脉血压和脉压呈U相关,其中收缩压143.4mmHg、平均动脉血压101mmHg和脉压66mmHg人群的死亡风险最低。多因素调整后,仅收缩期血压与死亡风险呈U相关,其中收缩期血压129mmHg人群的死亡风险最低。与收缩期血压129 mm Hg人群比较,收缩期血压低于107mmHg人群的全因死亡风险为1.08,高于154mmHg人群的死亡风险为1.27。特异性死亡风险分析显示,与收缩血压中段人群(107-154mmHg)相比,>154mmHg人群的心血管死亡风险增加51%,<107 mm Hg人群的非心血管死亡风险增加58%。这种U相关在敏感性以及亚组分析中仍保持。

研究发现,对于中国90岁以上高龄老年人群,其血压与死亡风险呈U相关。血压较高人群的心血管死亡风险增加,而较低人群的非心血管死亡风险增加,这一研究发现强调了在高龄老年人群中重新审视血压管理或制定具体的管理指南的重要性。

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    2018-07-10 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1848533, encodeId=fcbc18485331f, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 10 13:25:00 CST 2018, time=2018-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326928, encodeId=b6b032692883, content=根据该文的结果.老年人达标血压定在150mmHg是不合适的., beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ad162150, createdName=tjdsyyzg, createdTime=Mon Jun 25 17:00:51 CST 2018, time=2018-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=323077, encodeId=150e3230e7d4, content=学习了.获益匪浅.感谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Jun 10 14:48:49 CST 2018, time=2018-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255771, encodeId=fc4b1255e7196, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Fri Jun 08 01:25:00 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416073, encodeId=928e14160e31f, content=<a href='/topic/show?id=99fb1028231b' target=_blank style='color:#2F92EE;'>#高龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102823, encryptionId=99fb1028231b, topicName=高龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=307c3130149, createdName=xlysu, createdTime=Fri Jun 08 01:25:00 CST 2018, time=2018-06-08, status=1, ipAttribution=)]
    2018-06-25 tjdsyyzg

    根据该文的结果.老年人达标血压定在150mmHg是不合适的.

    0

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    2018-06-10 虈亣靌

    学习了.获益匪浅.感谢分享.

    0

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    2018-06-08 xlysu

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