BMJ:习惯性补充鱼油与心血管疾病死亡之间的关系

2020-03-08 MedSci原创 MedSci原创

本项研究旨在评估大量前瞻性队列中习惯性鱼油补充与心血管疾病(CVD)和死亡率的关系。

背景及目的: 本项研究旨在评估大量前瞻性队列中习惯性鱼油补充与心血管疾病(CVD)和死亡率的关系。

方法: 研究人员收集了在2006年至2010年之间共427678名年龄在40至69岁之间,无CVD或癌症的男性和女性,并随访至2018年底。所有参与者回答了习惯性使用补充剂(包括鱼油)的问题。主要结果指标是死亡率,CVD死亡率和CVD事件。

结果: 在基线时,427678名参与者中有133438名(31.2%)报告了习惯性使用鱼油补充剂的情况。习惯性使用鱼油与不使用鱼油的多因素调整后的所有危险因素的危险比分别为0.87(95%置信区间0.83至0.90),CVD死亡率为0.84(0.78至0.91)和CVD事件为0.93(0.90至0.96)。对于CVD事件,在患有高血压的患者中,这种关联似乎更强(P = 0.005)。

结论:习惯使用鱼油似乎与降低所有原因和CVD死亡率的风险有关。

原始出处:

Zhi-Hao Li. Et al. Associations of habitual fish oil supplementation with cardiovascular outcomes and all cause mortality: evidence from a large population based cohort study. BMJ. 2020.

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