Circulation:心肺复苏过程中平均舒张压≥25mmHg(婴儿)或≥30mmHg(满1岁)可提高患儿预后

2018-04-24 MedSci MedSci原创

基于实验室心肺复苏(CPR)研究和有限的提示CPR过程中存活率取决于获得合适的舒张压(DBP)的成人数据,美国心脏协会推荐用血压指导儿童CPR。但是在儿童CPR中,基于证据的血压目标值仍是CPR指南的一个重要知识缺陷。本研究纳入2013年7月1日-2016年6月31日期间所有在协助儿科急救护理研究中心重症病房进行胸外按压≥1min、并在CPR前后有侵袭性动脉血压监测的妊娠满37周、19岁以下的儿童

基于实验室心肺复苏(CPR)研究和有限的提示CPR过程中存活率取决于获得合适的舒张压(DBP)的成人数据,美国心脏协会推荐用血压指导儿童CPR。但是在儿童CPR中,基于证据的血压目标值仍是CPR指南的一个重要知识缺陷。

本研究纳入2013年7月1日-2016年6月31日期间所有在协助儿科急救护理研究中心重症病房进行胸外按压≥1min、并在CPR前后有侵袭性动脉血压监测的妊娠满37周、19岁以下的儿童。收集CPR期间的平均DBP和标准化心脏骤停数据。推测CPR过程中,婴儿DBP≥25mmHg、儿童(≥1岁)≥30mmHg与存活率相关。主要评估指标出院时的存活率。次要指标出院时神经预后良好的概率。

共分析了164名儿童CPR过程中的血压波形,1岁以下的有60%,60%的患儿有先心病,54%的患者进行过心脏手术。心脏骤停的主要原因是低血压(67%)、呼吸衰竭(44%)和心律失常(19%)。CPR的中位时间 8min(四分位 3-27min)。90%的患儿存活,其中68%的患儿恢复自主循环、22%的患者依赖体外生命支持。47%的患者获得出院,而且43%的患者出院时神经功能预后良好。有101位(62%)患儿平均DBP维持在25mmHg(婴儿)或30mmHg(满1岁)及以上,与存活率(校正相当风险 1.7;95% CI 1.2-2.6;p=0.007)和良好神经预后(1.6;95% CI 1.1-2.5;p=0.02)均相关。

本研究数据表明CPR过程中,平均DBP≥25mmHg(婴儿)或≥30mmHg(满1岁)可提高患儿出院的可能性、改善神经预后。

原始出处:

Robert A. Berg, et al.Association Between Diastolic Blood Pressure During Pediatric In-Hospital Cardiopulmonary Resuscitation and Survival.Circulation. April 24,2018.https://doi.org/10.1161/CIRCULATIONAHA.117.032270

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    2018-12-11 aids222
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    2018-04-26 smartxiuxiu

    0

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    2018-04-26 lizhou0204
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    2018-04-25 易水河

    很好.知之为知之

    0

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    2018-04-24 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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