Diabetes Care:无糖尿病人群的空腹血糖居然也影响心肌梗死!

2017-09-15 MedSci MedSci原创

近期,一项发表在杂志Diabetes Care上的研究评估了随时间变化的空腹血糖(FBG)水平变化及其对心肌梗死(MI)的潜在影响。此项前瞻性队列研究包括68,297名没有糖尿病的患者(平均年龄49岁),他们在2010年或2010年之前没有MI、中风和癌症史(此项研究分析的基线)。在2006年、2008年和2010年测量了受试者的FBG浓度。2006-2010年期间的FBG的变化曲线是此项研究的主

近期,一项发表在杂志Diabetes Care上的研究评估了随时间变化的空腹血糖(FBG)水平变化及其对心肌梗死(MI)的潜在影响。此项前瞻性队列研究包括68,297名没有糖尿病的患者(平均年龄49岁),他们在2010年或2010年之前没有MI、中风和癌症史(此项研究分析的基线)。在2006年、2008年和2010年测量了受试者的FBG浓度。2006-2010年期间的FBG的变化曲线是此项研究的主要对象,其通过潜在混合物建模来确定。事件性MI病例通过心脏病专家检查病历得到确认。最终,研究者们根据FBG范围和随时间变化的模式确定了五个离散的FBG轨迹:升高稳定(n = 3877),升高降低(n = 7,060),中等增加(n = 10,298),中等稳定(n = 40,352 ),低稳态(n = 6,710)。在4年的随访中,共记录了283例MI事件。对潜在的混杂因素如年龄、性别、生活方式因素、肥胖、病史、血压、血脂和C反应蛋白进行调整后,相对于中等稳定型(FBG范围为4.9〜5.1 mmol/L),升高稳定型(FBG范围为6.1〜6.3 mmol/L)的调整风险比(HR)为1.53(9

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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 15 08:50:22 CST 2017, time=2017-09-15, status=1, ipAttribution=)]
    2017-09-17 往日如昨

    继续学习中谢谢

    0

  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 15 08:50:22 CST 2017, time=2017-09-15, status=1, ipAttribution=)]
    2017-09-17 往日如昨

    学习了谢谢分享

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 15 08:50:22 CST 2017, time=2017-09-15, status=1, ipAttribution=)]
    2017-09-17 xuexin53

    学习

    0

  7. 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  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 15 08:50:22 CST 2017, time=2017-09-15, status=1, ipAttribution=)]
    2017-09-15 Y—xianghai

    学习了新知识

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 15 08:50:22 CST 2017, time=2017-09-15, status=1, ipAttribution=)]
    2017-09-15 135****7952平儿

    学了..........

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 15 08:50:22 CST 2017, time=2017-09-15, status=1, ipAttribution=)]
    2017-09-15 1e10c84am36(暂无匿称)

    文章很好.值得分享

    0

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