Ann Surg:腹股沟疝修补是否影响男性的生殖能力?

2017-07-23 MedSci MedSci原创

此前,虽然有研究间接评估了腹股沟疝修补对男性生殖力的影响,但这些研究均没有对男性生育的最终评估值进行研究。近期,一项发表在杂志Ann Surg上的研究调查了接受腹股沟疝修补术的患者是否与正常人群具有相同数量的子女。此项研究选取在1998年至2012年期间接受1次或多次腹股沟疝修复的32,621名年龄在18至55岁之间的男性患者,收集了5个丹麦综合登记册的资料。同时招募了相匹配的97,805个对照组

此前,虽然有研究间接评估了腹股沟疝修补对男性生殖力的影响,但这些研究均没有对男性生育的最终评估值进行研究。


近期,一项发表在杂志Ann Surg上的研究调查了接受腹股沟疝修补术的患者是否与正常人群具有相同数量的子女。

此项研究选取在1998年至2012年期间接受1次或多次腹股沟疝修复的32,621名年龄在18至55岁之间的男性患者,收集了5个丹麦综合登记册的资料。同时招募了相匹配的97,805个对照组,生育次数记录为主要结局。

此项研究结果显示:单侧手术的患者比对照组人群具有更多的子女(156例 vs. 147例,每1000人,P = 0.02),而双侧手术的患者与对照组具有相同数量的子女。单侧Lichtenstein手术导致患者子女人数的增加(161例 vs. 151例,每1000例患者,P = 0.009)。在手术后的任何一年中均没有发现子女数量的差异。同时,手术与第一胎子女之间的时间在对照组人群中更久(log-rank P = 0.003)。年龄最小的双侧手术患者(18-30岁)与对照人群的子女数量相同。

此项研究表明:使用Lichtenstein术式或腹腔镜手术进行腹股沟疝修补术的患者的子女数量并不比对照组人群少。因此,使用Lichtenstein的腹股沟疝修补术或腹腔镜手术不会损害男性的生育能力。

原始出处:
Kohl AP, Andresen K, Rosenberg J. Male Fertility After Inguinal Hernia Mesh Repair: A National Register Study. Ann Surg. 2017 Jul 12. doi: 10.1097/SLA.0000000000002423.

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    2017-07-25 hhh678

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    2017-07-24 hhh678

    henhao

    0

  5. 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    2017-07-24 137****9095

    henhao

    0

  6. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225452, encodeId=16382254520f, content=还是感觉上有所差异的不同 如何了解和认知, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Sun Jul 23 13:55:18 CST 2017, time=2017-07-23, status=1, ipAttribution=)]
    2017-07-24 1e0e5697m83(暂无匿称)

    henhao

    0

  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225452, encodeId=16382254520f, content=还是感觉上有所差异的不同 如何了解和认知, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Sun Jul 23 13:55:18 CST 2017, time=2017-07-23, status=1, ipAttribution=)]
    2017-07-24 1e0e5a1fm42(暂无匿称)

    henhao

    0

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    2017-07-24 139****0239

    henhao

    0

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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225452, encodeId=16382254520f, content=还是感觉上有所差异的不同 如何了解和认知, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Sun Jul 23 13:55:18 CST 2017, time=2017-07-23, status=1, ipAttribution=)]
    2017-07-23 184****9840

    学习了谢谢分享

    0

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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225452, encodeId=16382254520f, content=还是感觉上有所差异的不同 如何了解和认知, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Sun Jul 23 13:55:18 CST 2017, time=2017-07-23, status=1, ipAttribution=)]
    2017-07-23 雾夜芭蕾

    还是感觉上有所差异的不同 如何了解和认知

    0