JAMA Cardiol:右心室功能障碍的心力衰竭患者预后较差

2018-08-23 国际循环编辑部 国际循环

目前,关于普通人群右心室(RV)功能障碍的发病率和预后重要性的数据非常有限。近期,发表于JAMA的一项研究,针对社区老年患者展开队列试验,分析RV功能障碍的发病率及其与心力衰竭(HF)和死亡的关系。

目前,关于普通人群右心室(RV)功能障碍的发病率和预后重要性的数据非常有限。近期,发表于JAMA的一项研究,针对社区老年患者展开队列试验,分析RV功能障碍的发病率及其与心力衰竭(HF)和死亡的关系。

研究人员对社区动脉粥样硬化风险(ARIC)项目中的受试者进行横断面和事件时间分析,纳入参加第5次项目调查的1004例老年患者,给予三维和二维RV超声心动图检查。

在横断面分析中,研究人员按照ACCF/AHA的HF分级程度记录RV功能障碍的发生率,具体级别为:0级;A级,HF风险升高但无结构性心脏病或临床HF;B级,出现结构性心脏病但无临床HF;C级,出现HF。在事件时间分析中,研究人员以访问期间无HF受试者出现HF所致住院或全因死亡为主要终点。

1004例受试者的平均RVEF为53%。以0级受试者作为参考,共有103例无症状A级HF患者(15%)和27例B级HF患者(24%)出现RVEF异常。在所有基线无HF的患者中,RVEF降低与HF发作和死亡具有显著相关性(RVEF每降低5%:HR=1.20;95%CI:1.02~1.42;P=0.03)。

这项研究结果提示,RV功能障碍在HF进展中具有重要作用,三维超声心动图能更准确评估RV功能。

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    2018-08-24 邓启付

    三维超声心动图对心脏病变的诊断有重要价值。

    0

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    2018-08-23 huangshang9812

    学习了

    0

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