Osteoporos Int:哪种脂肪增加骨折风险?

2018-10-20 吴星 环球医学

2018年9月,伊朗学者发表在《Osteoporos Int》的一项观察性研究的系统评价和Meta分析,考察了膳食脂肪、饱和脂肪酸(SFAs)和单不饱和脂肪酸(MUFAs)摄入与骨折风险之间的相关性。

2018年9月,伊朗学者发表在《Osteoporos Int》的一项观察性研究的系统评价和Meta分析,考察了膳食脂肪、饱和脂肪酸(SFAs)和单不饱和脂肪酸(MUFAs)摄入与骨折风险之间的相关性。

总体膳食脂肪摄入可能影响骨折风险;然而,迄今为止报告的结果仍有冲突。此外,脂肪酸类型也极其关键。研究者旨在进行一项调查膳食脂肪摄入、SFAs、MUFAs与骨折风险相关性的文献的综合评价。

研究者对PubMed和Scopus进行了综合检索,发表的文献截至2018年1月7日。为了汇总效应大小,采用了随机效应模型(DerSimonian-Laird方法)。Cochrane Q检验用于探寻研究间异质性资源。6项研究符合Meta分析的入组标准。

研究者发现,总体膳食脂肪摄入与骨折风险之间无显着相关性(汇总效应大小,1.31;95% 置信区间[CI],0.95~1.79;P=0.09)。SFA摄入与髋部骨折风险之间具有显着的正相关性(汇总效应大小,1.79;95% CI,1.05~3.03;P=0.03)。动物来源的MUFAs与骨折风险之间也具有显着的正相关性(汇总效应大小,2.29;95% CI,1.50~3.50;P<0.0001)。

结果表明,SFAs摄入与髋部骨折风险之间有强烈的正相关性。此外,动物来源的MUFAs与骨折风险之间有显着的正相关性。

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    2018-10-22 wxl882001

    学习一下

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    2018-10-22 lsndxfj
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    2018-10-20 医者仁心5538

    学习了

    0

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    2018-10-20 wxl882001

    学习一下

    0

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