Neurology:多发性硬化症发病率和患病率的时间趋势!

2018-03-18 xing.T MedSci原创

由此可见,在这一大型的以人群为基础的MS队列中,研究人员发现MS的发病率稳定,患病率增加,后者在很大程度上反映了死亡率下降。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,研究人员试图通过研究多发性硬化症(MS)病例的发病率、死亡率、性别比例和地理分布,来更好地了解MS患病率增加的原因。

研究人员通过对健康管理数据应用验证算法,确定了加拿大安大略市1996年至2013年期间的MS病例。研究人员通过人口普查计算了该省年龄和性别标准化的患病率和发病率。计算了男性和女性发病率和患病率。

MS患病率增加到了69%,由1996年每1000人中的1.57(95%可信区间为1.54-1.59)(n=12155)增加到2013年的2.65(95%可信区间为2.62-2.68)(n=28192)。除了2010的增幅外,发病率保持相对稳定,2011年至2013年期间出现了随后的下降,尤其是年轻人和男性。死亡率下降了33%,从每1000人中的26.7(95%CI为23.5 - 30.3)到每1000人中的18(95% CI为16.4 - 19.8)。发病率性别比从1996年到2009年维持稳定,到2010年下降,到2103年部分回升。

由此可见,在这一大型的以人群为基础的MS队列中,研究人员发现MS的发病率稳定,患病率增加,后者在很大程度上反映了死亡率下降。

原始出处:

Dalia L. Rotstein, et al. Temporal trends in multiple sclerosis prevalence and incidence in a large population.neurology.2018. https://doi.org/10.1212/WNL.0000000000005331

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    2018-09-09 yinhl1978
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    2018-09-04 jml2009
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  7. 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    2018-03-18 忠诚向上

    好好学习天天向上

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sun Mar 18 13:11:27 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 忠诚向上

    好好学习天天向上

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2000360, encodeId=6f162000360d9, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sun Sep 09 01:47:00 CST 2018, time=2018-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1982996, encodeId=143119829962f, content=<a href='/topic/show?id=a7a7e359478' target=_blank style='color:#2F92EE;'>#硬化症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73594, encryptionId=a7a7e359478, topicName=硬化症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, 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createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sun Mar 18 13:11:27 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 秀红

    学习了

    0

  10. 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    2018-03-18 戒馋,懒,贪

    谢谢分享学习了

    0

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