Allergy:婴儿毛细支气管炎后哮喘的危险因素分析!

2017-11-05 xing.T MedSci原创

由此可见,在不到六个月年龄时患有毛细支气管炎的人群中,在其11-13岁时,被医生诊断为哮喘的风险是一般人群的两倍左右。母亲患有哮喘是11-13岁儿童发生哮喘的唯一独立的重要早年生活危险因素。

研究人员在小于24个月龄时发生毛细支气管炎参与者中进行了五项研究,随访超过10年,据报道特应性皮炎、家族性哮喘、生命早期暴露于烟草和鼻病毒是后期发生哮喘的早期生活危险因素。近日,过敏性疾病领域权威杂志Allergy上发表了一篇研究文章,该研究旨在评估婴儿早期因毛细支气管炎而住院的11-13岁儿童长期结局。

研究人员之前前瞻性地随访了不到六个月时因毛细支气管炎而住院的166名儿童,并且随访至5-7岁。目前的研究包括问卷调查、父母访谈,研究人员对138名11-13岁儿童进行支气管舒张试验的临床检查。

研究人员发现66%的毛细支气管炎病例是由呼吸道合胞病毒感染引起的,近半数的患者在早期生活中暴露于烟草烟雾中。在之前患过支气管炎的儿童中,有13%的儿童在11-13岁时被医生诊断为哮喘。母亲哮喘是婴儿早年生活中唯一的独立的危险因素(比值比为3.45,95%可信区间为1.07-11.74),在5-7岁时的过敏性鼻炎也是如此(比值比为4.06,95%可信区间为1.35-12.25)。

由此可见,在不到六个月年龄时患有毛细支气管炎的人群中,在其11-13岁时,被医生诊断为哮喘的风险是一般人群的两倍左右。母亲患有哮喘是11-13岁儿童发生哮喘的唯一独立的重要早年生活危险因素。

原始出处:

S. Törmänen,et al. Risk factors for asthma after infant bronchiolitis.Allergy. 2017. http://onlinelibrary.wiley.com/doi/10.1111/all.13347/full

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    2017-11-07 膀胱癌
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