Hypertension:先兆子痫后高血压表型如何?

2017-11-13 xing.T MedSci原创

总之,产后6至12周的ABPM显示先兆子痫女性持续性、夜间率和隐匿性高血压发生率较高。这一发现可能有助于确定哪些妇女应进行产后心血管风险管理。

先兆子痫与心血管和肾脏的风险增加有关。近日,心血管权威杂志Hypertension上发表了一篇研究文章,该前瞻性队列研究的目的是描述先兆子痫患者产后早期的血压(BP)表型。

在这项前瞻性队列研究中,研究人员招募了115名先兆子痫妇女和4名例正常妊娠妇女。在产后6至12周后,研究人员使用24小时动态血压监测(ABPM)评估了不同高血压表型的患病率,以及评估了盐敏感性风险和来自于ABPM参数的BP变异性。

在先兆子痫患者中,57.4%的患者有诊室高血压。先兆子痫患者(118.9±15/83.2±10.4mmHg)白天的动态血压明显高于对照者(104.8±7.9/71.6±5.3 mmHg;P<0.01)。夜间血压值组间差异相似。50%的先兆子痫患者在产后ABPM中仍然表现为高血压,其中24.3%的患者仍在接受降压治疗;17.9%患者为白大衣高血压和11.6%的患者为隐匿性高血压。在对照组中,2.8%的受试者有白大衣高血压;无隐匿性高血压或需要进行高血压治疗。非杓型高血压的患病率在先兆子痫组与对照组类似分别为59.8%和51.4%。血压盐敏感性高风险分在先兆子痫妇女中有所增加(48.6%),相比于对照者(17.1%),P<0.01。

总之,产后6至12周的ABPM显示先兆子痫女性持续性、夜间率和隐匿性高血压发生率较高。这一发现可能有助于确定哪些妇女应进行产后心血管风险管理

原始出处:

Agnès Ditisheim, et al. Prevalence of Hypertensive Phenotypes After Preeclampsia A Prospective Cohort Study.Hypertension.2017. https://doi.org/10.1161/HYPERTENSIONAHA.117.09799

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    2018-09-14 feather89
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    2017-11-15 tastas
  5. [GetPortalCommentsPageByObjectIdResponse(id=2038782, encodeId=918e2038e8204, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Mon Apr 02 05:13:00 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726876, encodeId=1f031e26876be, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Sep 14 08:13:00 CST 2018, time=2018-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501226, encodeId=608915012266f, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Wed Nov 15 14:13:00 CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1535156, encodeId=9cee1535156a5, content=<a href='/topic/show?id=099f9020145' target=_blank style='color:#2F92EE;'>#表型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90201, encryptionId=099f9020145, topicName=表型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b6412593156, createdName=tastas, createdTime=Wed Nov 15 14:13:00 CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261233, encodeId=760f26123370, content=好文章大家共同分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Tue Nov 14 10:47:15 CST 2017, time=2017-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261108, encodeId=0304261108e1, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Nov 13 23:35:46 CST 2017, time=2017-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261100, encodeId=fae926110089, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Mon Nov 13 23:27:04 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
    2017-11-14 明天会更好!

    好文章大家共同分享!

    0

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    2017-11-13 清风拂面

    学习了.谢谢分享

    0

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    2017-11-13 Y—xianghai

    学习了新知识

    0

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