Diabetes Care:无论站立或行走,都能显著改善绝经后妇女餐后血糖代谢

2015-12-09 MedSci MedSci原创

2015年世界糖尿病年会,英国莱斯特大学的Henson医学教授发表一项最新研究——久坐后每半小时站立5分钟能够显著改善超重、绝经后妇女糖尿病前期的餐后血糖代谢。Henson教授指出,既往的研究均表明,通过散步等活动方式消耗能量以达到降低血糖和胰岛素的目的。但是,最新研究发现,无论是站立还是散步等运动均能有效降低血糖,且站立与行走的效果基本相似,二者之间没有明显差异。越来越多的研究表明,无论是行走还


2015年世界糖尿病年会,英国莱斯特大学的Henson医学教授发表一项最新研究——久坐后每半小时站立5分钟能够显著改善超重、绝经后妇女糖尿病前期的餐后血糖代谢。

Henson教授指出,既往的研究均表明,通过散步等活动方式消耗能量以达到降低血糖和胰岛素的目的。但是,最新研究发现,无论是站立还是散步等运动均能有效降低血糖,且站立与行走的效果基本相似,二者之间没有明显差异。

越来越多的研究表明,无论是行走还是站立工作均能增加能量消耗,以达到降低血糖的目的。总而言之,减少久坐是有益的。

坐、站立、行走

研究共纳入30例绝经后妇女,伴有葡萄糖糖耐量异常——口服葡萄糖耐量试验餐后血糖在7.8-11.1mmol/L;糖化血红蛋白HbA1c在5.7%-6.4%。

研究方法:所有试验参与者在上午8:00开始进行试验:所有参与者被要求安静地坐了30分钟,然后在上午9点给予早餐(58%的脂肪,26%的碳水化合物,16%蛋白质),中午给予相同的午餐,所有参与者均在餐后30,60,120,180以及210分钟时抽取血样。

试验分三组:一组简单地静坐7.5小时(盥洗室访问是经由轮椅制造);第二组每静坐30分钟,站立5分钟;第三组没静坐30分钟,在跑步机上走5分钟。所有参与者第二天接受前天完全相同的试验。

研究结果表明:

1.与不间断久坐相比,久坐后站立能够减少餐后血糖升高34%(P=0.022),久坐后步行减少餐后血糖升高28%(P=0.009);2.与不间断久坐相比,久坐后站立餐后胰岛素浓度升高20%(P=0.045),久坐后步行餐后胰岛素浓度升高37%(P=0.008);3.与不间断久坐相比,第二天久坐后站立血糖水平降低19%(P=0.039),久坐后步行血糖水平降低17%(P=0.027);4.与第一天相比,第二天餐后血糖水平在站立和步行状态下没有明显差异(P=0.877);5.与第一天相比,第二天胰岛素水平反应在站立组没有明显改变,而步行组仍有降低(P=.038);6.第一天,站立组和步行组没有明显差异(P=.529)

Cefalu教授兴奋的讲到,这项研究是令人不可思议的,当你仅仅通过间断站打破久坐即能降低血糖和胰岛素是多么令人激动。这将为公共卫生提供巨大的益处。这项研究不仅对绝经前妇女有益,对其他超体重和肥胖患者血糖代谢可能也有益。当然,这并不能否认运动的重要性

原始出处:

Henson J, Davies MJ, Bodicoat DH, Edwardson CL, Gill JM, Stensel DJ, Tolfrey K, Dunstan DW, Khunti K, Yates T.Breaking Up Prolonged Sitting With Standing or Walking Attenuates the Postprandial Metabolic Response in Postmenopausal Women: A Randomized Acute Study. Diabetes Care. 2015 Dec 1. pii: dc151240.

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  4. [GetPortalCommentsPageByObjectIdResponse(id=1637229, encodeId=183b163e22960, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Mar 31 02:09:00 CST 2016, time=2016-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901331, encodeId=806f19013313d, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Mon Feb 29 11:09:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759614, encodeId=58e81e5961425, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Mon Mar 14 20:09:00 CST 2016, time=2016-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48574, encodeId=8889485e42e, content=好文章,值得看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, 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channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101175, encryptionId=019e1011e589, topicName=餐后血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76df8418429, createdName=gjsgj, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631504, encodeId=2657163150452, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45522, encodeId=46854552229, content=有推广意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24721662825, createdName=1ddf23d5m57(暂无匿称), createdTime=Fri Dec 11 07:51:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
    2015-12-26 hixiaoluo

    好文章,值得看。

    0

  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24721662825, createdName=1ddf23d5m57(暂无匿称), createdTime=Fri Dec 11 07:51:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1637229, encodeId=183b163e22960, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Mar 31 02:09:00 CST 2016, time=2016-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901331, encodeId=806f19013313d, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Mon Feb 29 11:09:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759614, encodeId=58e81e5961425, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Mon Mar 14 20:09:00 CST 2016, time=2016-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48574, encodeId=8889485e42e, content=好文章,值得看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 17:36:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257032, encodeId=0c07125e032b3, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331994, encodeId=cafb13319946d, content=<a href='/topic/show?id=0ab6e8887cc' target=_blank style='color:#2F92EE;'>#绝经后妇女#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78887, encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360581, encodeId=4fe6136058100, content=<a href='/topic/show?id=16a6e66155b' target=_blank style='color:#2F92EE;'>#糖代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76615, encryptionId=16a6e66155b, topicName=糖代谢)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488446, encodeId=c6e9148844699, content=<a href='/topic/show?id=019e1011e589' target=_blank style='color:#2F92EE;'>#餐后血糖#</a>, beContent=null, objectType=article, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24721662825, createdName=1ddf23d5m57(暂无匿称), createdTime=Fri Dec 11 07:51:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
  7. 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createdBy=0045169, createdName=木头人513, createdTime=Mon Feb 29 11:09:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759614, encodeId=58e81e5961425, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Mon Mar 14 20:09:00 CST 2016, time=2016-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48574, encodeId=8889485e42e, content=好文章,值得看。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, 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encryptionId=0ab6e8887cc, topicName=绝经后妇女)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360581, encodeId=4fe6136058100, content=<a href='/topic/show?id=16a6e66155b' target=_blank style='color:#2F92EE;'>#糖代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76615, encryptionId=16a6e66155b, topicName=糖代谢)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488446, encodeId=c6e9148844699, content=<a href='/topic/show?id=019e1011e589' target=_blank style='color:#2F92EE;'>#餐后血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101175, encryptionId=019e1011e589, topicName=餐后血糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76df8418429, createdName=gjsgj, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631504, encodeId=2657163150452, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Fri Dec 11 14:09:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45522, encodeId=46854552229, content=有推广意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24721662825, createdName=1ddf23d5m57(暂无匿称), createdTime=Fri Dec 11 07:51:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
    2015-12-11 zz70
  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24721662825, createdName=1ddf23d5m57(暂无匿称), createdTime=Fri Dec 11 07:51:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24721662825, createdName=1ddf23d5m57(暂无匿称), createdTime=Fri Dec 11 07:51:00 CST 2015, time=2015-12-11, status=1, ipAttribution=)]
    2015-12-11 zxxiang
  10. 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    2015-12-11 1ddf23d5m57(暂无匿称)

    有推广意义

    0

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