Crit Care Med:创伤性脑损伤可以影响心脏收缩功能

2017-04-15 MedSci MedSci原创

此前有研究表明,创伤性脑损伤可能会影响心脏功能。近期,一项发表在杂志Crit Care Med上的研究旨在确定中重度创伤性脑损伤患者发生收缩功能障碍的频率、进程和入院的危险因素。此项研究为前瞻性队列研究。在中重度创伤性脑损伤后1天内和第1周内进行经胸超声心动图检查;轻度创伤性脑损伤后1天内进行经胸超声心动图(对照组)。通过经胸超声心动图评估心脏收缩功能,收缩功能障碍定义为射血分数小于25%。多变量

此前有研究表明,创伤性脑损伤可能会影响心脏功能。近期,一项发表在杂志Crit Care Med上的研究旨在确定中重度创伤性脑损伤患者发生收缩功能障碍的频率、进程和入院的危险因素。


此项研究为前瞻性队列研究。在中重度创伤性脑损伤后1天内和第1周内进行经胸超声心动图检查;轻度创伤性脑损伤后1天内进行经胸超声心动图(对照组)。

通过经胸超声心动图评估心脏收缩功能,收缩功能障碍定义为射血分数小于25%。多变量泊松回归模型检查收缩功能障碍的入院危险因素。采用经胸超声心动图评估32例独立中重度创伤性脑损伤患者和32例轻度创伤性脑损伤患者的收缩功能(对照组)。 

此项研究结果显示:7例(22%)中重度创伤性脑损伤患者和0例(0%)轻度创伤性脑损伤患者在损伤后第1天内发生心脏收缩功能障碍(p <0.01)。

所有患有早期收缩功能障碍的患者在1周内恢复。年龄较小(相对风险为0.87; 95%CI,0.79-0.94;年龄增加1岁)以及格拉斯哥昏迷量表评分较低(相对危险度为0.34;95%CI为0.20-0.58;格拉斯哥增加1分)与中重度创伤性脑损伤患者发生收缩功能障碍独立相关。

此项研究表明:早期收缩功能障碍可能发生在以前健康的中重度创伤性脑损伤患者,并且在住院的第一周是可逆的。年龄较小和入院时格拉斯哥昏迷评分与中重度创伤性脑损伤后收缩功能障碍的发生独立相关。

原始出处:
Krishnamoorthy V, Rowhani-Rahbar A, et al. Early Systolic Dysfunction Following Traumatic Brain Injury: A Cohort Study. Crit Care Med. 2017 Apr 10. doi: 10.1097/CCM.0000000000002404.

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    2017-10-19 amyloid
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    2017-04-19 成恩

    我想要学习啊

    0

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    2017-04-16 明天会更好!

    希望大家一起来学习!

    0

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    2017-04-15 flysky120

    谢谢,学习新知识了

    0

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    2017-04-15 胖红

    学习了很多的事情,

    0

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