Eur Respir J:住院患者呼吸困难、死亡率和卫生资源利用之间的关联

2021-03-14 MedSci原创 MedSci原创

任何级别的呼吸困难均与死亡风险增加相关。护理人员可以迅速收集患者呼吸困难的数据,这可能有助于更好地进行监测或采取干预措施,从而降低患者死亡率和发病率。

每10例患者中就有1例在入院时出现呼吸困难,但呼吸困难与患者预后之间的关系尚未明确。

近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,研究人员试图明确入院时呼吸困难是否可以预测患者结局。

研究人员在一个教学医院中心进行了一项回顾性队列研究,分析了67362例连续入院患者的呼吸困难、疼痛和结局数据。在护士进行的初始患者评估中,患者使用0到10的等级(10=难以忍受)对“呼吸不适”进行了评分。患者在入院时报告了呼吸困难,并回忆入院前24小时内经历的呼吸困难。结局包括住院死亡率、2年死亡率、住院时间、需要快速反应系统激活、转移到重症监护室、出院后接受扩展护理以及7天和30天再次入院。

报告有呼吸困难的患者在住院期间死亡的风险增加;呼吸困难程度越严重,死亡风险越大(呼吸困难=0,医院死亡率为0.8%;呼吸困难=1-3,死亡率为2.5%;呼吸困难≥4,死亡率为3.7%,p<0.001)。在对患者合并症、人口统计学和疾病严重性进行调整后,呼吸困难的增加仍与住院患者的死亡率相关(呼吸困难=1-3,aOR为2.1,95%CI为1.7-2.6;呼吸困难=3-4,aOR为3.1,95%CI为2.4-3.9)。疼痛并不能预测增加的死亡率。报告呼吸困难的患者还使用了更多的医院资源,更有可能再次入院,并在2年内死亡风险增加(呼吸困难=1-3,调整后的HR 为1.5,95%CI为1.3-1.6;呼吸困难≥4,调整的HR为1.7、95%CI为1.5-1.8)。

由此可见,任何级别的呼吸困难均与死亡风险增加相关。护理人员可以迅速收集患者呼吸困难的数据,这可能有助于更好地进行监测或采取干预措施,从而降低患者死亡率和发病率。

原始出处:

Jennifer P. Stevens,et al.Association of dyspnea, mortality, and resource use in hospitalised patients.Eur Respir J.2021.https://erj.ersjournals.com/content/early/2021/01/21/13993003.02107-2019

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1281887, encodeId=a76c128188e79, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Tue Mar 16 07:54:52 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948464, encodeId=1e9794846447, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Mon Mar 15 21:14:46 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948287, encodeId=c18a94828e7b, content=高层次研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Mar 15 10:06:58 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948152, encodeId=af87948152f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210309/3ebed07d7c624aadaefeed82ed1b9c54/df9b06b299a24411bd48847eb8c73660.jpg, createdBy=6b342463583, createdName=124219b2m20暂无昵称, createdTime=Sun Mar 14 19:22:59 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948131, encodeId=85b99481313e, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Mar 14 17:24:11 CST 2021, time=2021-03-14, status=1, ipAttribution=)]
    2021-03-15 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1281887, encodeId=a76c128188e79, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Tue Mar 16 07:54:52 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948464, encodeId=1e9794846447, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Mon Mar 15 21:14:46 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948287, encodeId=c18a94828e7b, content=高层次研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Mar 15 10:06:58 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948152, encodeId=af87948152f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210309/3ebed07d7c624aadaefeed82ed1b9c54/df9b06b299a24411bd48847eb8c73660.jpg, createdBy=6b342463583, createdName=124219b2m20暂无昵称, createdTime=Sun Mar 14 19:22:59 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948131, encodeId=85b99481313e, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Mar 14 17:24:11 CST 2021, time=2021-03-14, status=1, ipAttribution=)]
    2021-03-15 carrotlyl

    高层次研究

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1281887, encodeId=a76c128188e79, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Tue Mar 16 07:54:52 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948464, encodeId=1e9794846447, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Mon Mar 15 21:14:46 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948287, encodeId=c18a94828e7b, content=高层次研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Mar 15 10:06:58 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948152, encodeId=af87948152f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210309/3ebed07d7c624aadaefeed82ed1b9c54/df9b06b299a24411bd48847eb8c73660.jpg, createdBy=6b342463583, createdName=124219b2m20暂无昵称, createdTime=Sun Mar 14 19:22:59 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948131, encodeId=85b99481313e, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Mar 14 17:24:11 CST 2021, time=2021-03-14, status=1, ipAttribution=)]
    2021-03-14 124219b2m20暂无昵称

    学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1281887, encodeId=a76c128188e79, content=<a href='/topic/show?id=21753963364' target=_blank style='color:#2F92EE;'>#呼吸困难#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39633, encryptionId=21753963364, topicName=呼吸困难)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=365d170, createdName=chenwq08, createdTime=Tue Mar 16 07:54:52 CST 2021, time=2021-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948464, encodeId=1e9794846447, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Mon Mar 15 21:14:46 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948287, encodeId=c18a94828e7b, content=高层次研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Mar 15 10:06:58 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948152, encodeId=af87948152f2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210309/3ebed07d7c624aadaefeed82ed1b9c54/df9b06b299a24411bd48847eb8c73660.jpg, createdBy=6b342463583, createdName=124219b2m20暂无昵称, createdTime=Sun Mar 14 19:22:59 CST 2021, time=2021-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948131, encodeId=85b99481313e, content=好文章!, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Mar 14 17:24:11 CST 2021, time=2021-03-14, status=1, ipAttribution=)]
    2021-03-14 jyzxjiangqin

    好文章!

    0

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