JAMA Pediatrics:早产儿呼吸护理,无创通气或优于机械通气

2021-07-08 MedSci原创 MedSci原创

关注早产儿!

据数据显示,全世界近11%的分娩为早产,每年影响1500万例分娩。这些不成熟的婴儿患各种并发症风险升高,包括支气管肺发育不良,脑出血,坏死性小肠结肠炎,败血症和视网膜病变等,且与长期不良结果相关。

CCO

对于早产儿来说,机械通气可能会对肺部和神经发育产生不利影响。为了降低这些风险,在过去的20年,医生一直在探索和研究无创通气,例如针对这些婴儿的持续气道正压通气( CPAP )治疗。2008 年、2010 年和 2011 年发表的大型研究表明,机械通气并不优于无创通气,实际上可能涉及更多风险,从而支持了无创通气的有效性。虽然,早产儿的呼吸支持模式可能早已改变,但并没有研究真正量化过这一点。

近日,发表在JAMA Pediatrics杂志的一项研究评估了美国早产儿机械通气和无创通气支持的时间变化。结果发现, 2008 年到 2018 年,早产儿使用机械通气的比例减少 10% 以上。同时,早产儿使用无创通气有所增加。

Hatch 及其同事评估了2个大型美国国家数据集以及包括超过 100 万早产儿的队列研究,确认了无创通气在实践中的变化。研究人员查看200811日至20181231日期间有关妊娠 22 周至 34 周之间出生婴儿的呼吸支持类型的数据。

结果显示,早产儿的机械通气利用率从 2008 年的 29.4% 下降到 2018 年的 18.5%。在全国范围内,这些变化与在研究期间接受机械通气的婴儿减少了约 30,000 名。随着机械通气婴儿数量的下降,机械通气婴儿使用机械呼吸机的时间也随之下降。

此外,研究人员发现,无创通气的使用从2008年的57.9%的婴儿增加到2018年的67.4%。随着持续气道正压和鼻腔间歇性正压通气的使用增加,从2008年到2018年,呼吸支持的平均持续时间从13.8天增加到15.4天。

总之,这项研究结果表明,早产儿接受呼吸支持从 2008 年到 2018 年发生了显著变化,机械通气的使用和持续时间减少,无创通气的使用和持续时间增加,且呼吸支持持续时间总体增加。

原始出处

L. Dupree Hatch et al, Changes in Use of Respiratory Support for Preterm Infants in the US, 2008-2018, JAMA Pediatrics (2021). DOI: 10.1001/jamapediatrics.2021.1921

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1639801, encodeId=33e41639801bd, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Sep 26 02:54:47 CST 2021, time=2021-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958559, encodeId=f98119585593c, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Jun 24 03:54:47 CST 2022, time=2022-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729027, encodeId=d8331e29027fe, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Oct 31 18:54:47 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495708, encodeId=28d91495e082a, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Jul 10 02:54:47 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036732, encodeId=a2831036e3231, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Jul 08 14:54:47 CST 2021, time=2021-07-08, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1639801, encodeId=33e41639801bd, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Sep 26 02:54:47 CST 2021, time=2021-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958559, encodeId=f98119585593c, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Jun 24 03:54:47 CST 2022, time=2022-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729027, encodeId=d8331e29027fe, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Oct 31 18:54:47 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495708, encodeId=28d91495e082a, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Jul 10 02:54:47 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036732, encodeId=a2831036e3231, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Jul 08 14:54:47 CST 2021, time=2021-07-08, status=1, ipAttribution=)]
    2022-06-24 hbwxf
  3. [GetPortalCommentsPageByObjectIdResponse(id=1639801, encodeId=33e41639801bd, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Sep 26 02:54:47 CST 2021, time=2021-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958559, encodeId=f98119585593c, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Jun 24 03:54:47 CST 2022, time=2022-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729027, encodeId=d8331e29027fe, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Oct 31 18:54:47 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495708, encodeId=28d91495e082a, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Jul 10 02:54:47 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036732, encodeId=a2831036e3231, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Jul 08 14:54:47 CST 2021, time=2021-07-08, status=1, ipAttribution=)]
    2021-10-31 feather89
  4. [GetPortalCommentsPageByObjectIdResponse(id=1639801, encodeId=33e41639801bd, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Sep 26 02:54:47 CST 2021, time=2021-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958559, encodeId=f98119585593c, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Jun 24 03:54:47 CST 2022, time=2022-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729027, encodeId=d8331e29027fe, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Oct 31 18:54:47 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495708, encodeId=28d91495e082a, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Jul 10 02:54:47 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036732, encodeId=a2831036e3231, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Jul 08 14:54:47 CST 2021, time=2021-07-08, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1639801, encodeId=33e41639801bd, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun Sep 26 02:54:47 CST 2021, time=2021-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958559, encodeId=f98119585593c, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Jun 24 03:54:47 CST 2022, time=2022-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1729027, encodeId=d8331e29027fe, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Oct 31 18:54:47 CST 2021, time=2021-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1495708, encodeId=28d91495e082a, content=<a href='/topic/show?id=aa1e58914c2' target=_blank style='color:#2F92EE;'>#无创通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58914, encryptionId=aa1e58914c2, topicName=无创通气)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e489186998, createdName=yhy100203, createdTime=Sat Jul 10 02:54:47 CST 2021, time=2021-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036732, encodeId=a2831036e3231, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Jul 08 14:54:47 CST 2021, time=2021-07-08, status=1, ipAttribution=)]
    2021-07-08 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

相关资讯

JAMA Pediatrics:早产儿或低出生体重与成年后智商有关

尽管极早产儿相对较少,占全世界所有早产儿的5.2%。据数据显示,这些不成熟的婴儿患各种并发症风险升高,包括支气管肺发育不良,脑出血,坏死性小肠结肠炎,败血症和视网膜病变等,且与长期不良结果相关。

PLOS Medicine:人乳头瘤病毒感染可增加早产风险

人乳头瘤病毒 (HPV) 感染是育龄妇女最常见的生殖器感染。持续性生殖器感染高危 HPV 与宫颈癌及其前体宫颈上皮内瘤变 (CIN)有关。

Dev Cogn Neurosci:运动有助于早产儿的认知发展

胎龄在37足周以前出生的活产婴儿称为早产儿或未成熟儿。其出生体重大部分在2500g以下,头围在33cm以下。

NEJM:尽早开展袋鼠妈妈护理有助于降低出生低体重儿死亡风险

出生体重在1.0-1.799千克之间的低出生体重儿,立即接受袋鼠妈妈护理可降低患儿28天死亡风险

Stroke:超210万人群队列研究:早产儿在成年后患中风的风险要高 42%!

中风是世界上第三大死亡原因。有研究显示,我国成年人中风的发生率约为25%,即每4个人中就有一人在一生中会遭遇中风。

上海交通大学发现分娩启动机制,有望提供新的药物靶标防治早产

这项分娩启动机制最新研究成果将为早产防治提供了新策略,有望为阻断分娩启动提供新的药物靶标,从而为早产防治提供新的干预手段。