Lancet:CBT 可缓解难治性抑郁症状

2012-12-21 Lancet CMT 程蓓 编译

  英国一项随机对照研究显示,在常规治疗(包括使用抗抑郁药)的基础上,采用认知行为治疗(CBT)可有效缓解难治性抑郁症患者的症状。论文12月7日在线发表于《柳叶刀》(Lancet)杂志。   研究纳入469例难治性抑郁症患者,年龄为18~75岁,将其随机分成常规治疗组(n=235)和常规治疗联合CBT组(n=234),并随访12个月。主要的临床转归是,与贝克抑郁症量表(BDI)评分基线相比,在随

  英国一项随机对照研究显示,在常规治疗(包括使用抗抑郁药)的基础上,采用认知行为治疗(CBT)可有效缓解难治性抑郁症患者的症状。论文12月7日在线发表于《柳叶刀》(Lancet)杂志。

  研究纳入469例难治性抑郁症患者,年龄为18~75岁,将其随机分成常规治疗组(n=235)和常规治疗联合CBT组(n=234),并随访12个月。主要的临床转归是,与贝克抑郁症量表(BDI)评分基线相比,在随访6个月时患者的抑郁症状缓解至少50%(按照BDI评分)。

  结果显示,在随访6个月时,常规治疗组达到主要临床转归者有46例(22%)。与之相比,常规治疗联合CBT组则有95例(46%,比值比为3.26,P<0.001)。

抑郁症相关的拓展阅读:


In The Lancet , Nicola Wiles and colleagues 1 answer the call for further study of the efficacy of psychotherapy for patients with treatment resistant depression. 2 They recruited 469 patients (aged 18—75 years) with treatment-resistant depression from 73 UK general practices and randomly assigned them to one of two groups: usual care (n=235) or cognitive-behavioural therapy (CBT) in addition to usual care (n=234). Patients were followed up for 12 months. Studies such as this one are much needed becau ...
    

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    2013-06-21 howi
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    2012-12-23 freve
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    2012-12-23 gds2013

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