ASCO 会议速递:多发性骨髓瘤领域重要研究汇总

2023-05-16 网络 网络 发表于上海

多发性骨髓瘤领域重要研究汇总

前言

第59届美国临床肿瘤学会(ASCO)年会将于美国芝加哥当地时间6月2日至6日举行。本届ASCO年会MM领域者重磅研究有哪些呢,一起来看看吧。

 

摘要号:8010—MM-CAR-T

标题:Long-term remission and survival in patients with relapsed or refractory multiple myeloma after treatment of LCAR-B38M CAR-T: At least 5-year follow-up in LEGEND-2.

报告人:糜坚青

单位:上海交通大学医学院附属瑞金医院上海血液研究所、医学基因组学国家重点实验室

 

摘要号:8013-MM

标题:Impact of bridging therapy (BT) on outcome of relapsed refractory multiple myeloma (RRMM) with Ide-cel CAR T-cell therapy: Real-world experience from the US myeloma CAR T consortium.

报告人:Aimaz Afrough

单位:Simmons Comprehensive Cancer Center, UT Southwestern Medical Center

 

摘要号:8017-MM

标题:Final results of pilot trial to evaluate anti-PD1 and 8 Gy in 1 fx for relapsed refractory multiple myeloma.

报告人:Mohammad Khan

单位:Emory University

 

摘要号:8020-MM

标题:Analysis of infections and parameters of humoral immunity in patients (pts) with relapsed/refractory multiple myeloma (RRMM) treated with talquetamab (tal) monotherapy in MonumenTAL-1.

报告人:Paula Rodríguez-Otero

单位:Clínica Universidad de Navarra, CIMA, CIBERONC, IDISNA

 

摘要号:8029-MM

标题:Phase 2 study of abatacept, ixazomib, and dexamethasone in patients with relapsed/refractory multiple myeloma.

报告人:Khalid Shalaby

单位:Roswell Park Comprehensive Cancer Center

 

摘要号:8030-MM

标题:Phase 2 study of abatacept, ixazomib, and dexamethasone in patients with relapsed/refractory multiple myeloma.

报告人:Khalid Shalaby

单位:Roswell Park Comprehensive Cancer Center

 

摘要号:8036-MM

标题:Pivotal phase 2 MonumenTAL-1 results of talquetamab (tal), a GPRC5DxCD3 bispecific antibody (BsAb), for relapsed/refractory multiple myeloma (RRMM).

报告人:Carolina Schinke

单位:Myeloma Center, University of Arkansas for Medical Sciences

 

摘要号:8040—MM—药物疗效

标题:Efficacy and safety of elranatamab by age and frailty in patients (pts) with relapsed/refractory multiple (RRMM): A subgroup analysis from MagnetisMM-3.

报告人:Noopur Raje

单位:Massachusetts General Hospital Cancer Center, Harvard Medical School

 

摘要号:8041—MM—给药

标题:Efficacy, safety, pharmacokinetic (PK), and pharmacodynamic (PD) support for talquetamab (tal) QW and Q2W dosing in patients (pts) with relapsed/refractory multiple myeloma (RRMM): Analyses from MonumenTAL-1.

报告人:Xuewen Ma

单位:Janssen Research & Development

 

摘要号:TPS8063

标题:A first-in-human phase 1, multicenter, open-label study of CB-011, a next-generation CRISPR-genome edited allogeneic anti-BCMA immune-cloaked CAR-T cell therapy, in patients with relapsed/refractory multiple myeloma (CAMMOUFLAGE trial).

报告人:Jesus Berdeja

单位:Sarah Cannon Research Institute

 

摘要号:TPS8068—新药--MM

标题:OMNIA-2: Phase I/II study of ANV419, an IL-2R-βγ targeted antibody-IL-2 fusion protein, in patients with relapsed or refractory multiple myeloma.

报告人:Dagmar Hess

单位:Kantonsspital St. Gallen

 

摘要号:TPS8070--MM

标题:A phase 3, two-stage, randomized study of mezigdomide, carfilzomib, and dexamethasone (MeziKd) versus carfilzomib and dexamethasone (Kd) in relapsed/refractory multiple myeloma (RRMM): SUCCESSOR-2.

报告人:Paul Richardson

单位:Dana-Farber Cancer Institute

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