Open Heart:戒烟可降低CVD风险,甚至达到从不吸烟者水平

2016-10-25 MedSci MedSci原创

研究人员报告说,在芬兰的工作年龄人口中,过去或现在吸烟,对个体心血管(CVD)危险因素有临床上的较小的显著性影响。研究人员在Open Heart中写道,“在工作年龄戒烟可以减少CVD风险,甚至可以降低到与从不吸烟者相当水平。”参与者为3548名31-46岁人群。使用个体心血管疾病的危险因素、Framingham风险评分和冠心病风险评估系统(SCORE)计算在下一个十年中,患者的绝对CVD事件风险。

研究人员报告说,在芬兰的工作年龄人口中,过去或现在吸烟,对个体心血管(CVD)危险因素有临床上的较小的显著性影响。

研究人员在Open Heart中写道,“在工作年龄戒烟可以减少CVD风险,甚至可以降低到与从不吸烟者相当水平。”

参与者为3548名31-46岁人群。使用个体心血管疾病的危险因素、Framingham风险评分和冠心病风险评估系统(SCORE)计算在下一个十年中,患者的绝对CVD事件风险。

研究人员发现,从不吸烟者、最近戒烟者和以前吸烟者之间的心血管风险无显著差异。

在男性中,平均Framingham风险评分在46岁时,不吸烟者为7.5%,戒烟者为7.4%,以前吸烟者为8.1%,当前吸烟者为14.7%。

在女性中,平均Framingham风险评分在46岁时,不吸烟者为3.3%,戒烟者为3%,以前吸烟者为3.2%,当前吸烟者为5.9%。

研究人员还报告,对男性和女性使用SCORE,发现吸烟和致命性心血管事件风险增加之间的关联。

当研究人员分析随着时间的推移吸烟行为的变化,他们发现,30岁前戒烟的超过80%的个体,在46岁时,仍不吸烟。

总体而言,吸烟者与不吸烟者相比,体重指数和腰围增加。在男性中,目前吸烟者与从不吸烟者相比,有较高的总胆固醇和甘油三酯;在女性中,目前吸烟者与从不吸烟者相比,有较差的血脂水平、更高的低密度脂蛋白和甘油三酯,和较低的高密度脂蛋白。

女性目前吸烟者或最近戒烟者更容易使用降血脂药物。在男性中,先前吸烟者有最高的收缩压和舒张压,更容易使用抗高血压的药物。在女性中,不吸烟者有最高的收缩期血压水平。在男性中,先前和目前吸烟者的2型糖尿病的发病率是相似的;在女性中,也没有观察到差异。

研究人员写道:“与不吸烟者相比,吸烟者和戒烟者的吸烟相关危险因素很多;然而,这些主要的差异是很小的,不可能有重大的临床意义。”

原始出处:

Keto J, et al. Cardiovascular disease risk factors in relation to smoking behaviour and history: a population-based cohort study.Open Heart. 2016;doi:10.1136/openhrt-2015-000358.

Quitting smoking at working age may reduce CVD risk to same level as never-smokers
.Healio.October 24, 2016

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    2016-11-28 爆笑小医
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    2016-10-27 zhaojie88
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    2016-10-27 slcumt
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