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JCO：中国研究团队发现腹腔镜远端胃切除术治疗胃癌是安全的

2016-02-29 MedSci MedSci原创

胃癌胃部切除术淋巴结切除术
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 胃癌是世界第三大癌症。在中国，每年有超过四十万病人受到胃癌的危害。对于局部晚期胃癌患者来说，目前手术彻底切除仍然是现有治疗方案的基石。目前治疗晚期胃癌的腹腔镜远端胃部切除术联合D2淋巴切除术的安全性和有效性尚存在争议。来自中国的科研团队进行了一项随机对照试验来比较腹腔镜的和传统的开放式远端胃切除术以及D2淋巴结切除术治疗晚期胃癌的效果和安全性。 在2012年9月到2014年1

胃癌是世界第三大癌症。在中国，每年有超过四十万病人受到胃癌的危害。对于局部晚期胃癌患者来说，目前手术彻底切除仍然是现有治疗方案的基石。目前治疗晚期胃癌的腹腔镜远端胃部切除术联合D2淋巴切除术的安全性和有效性尚存在争议。来自中国的科研团队进行了一项随机对照试验来比较腹腔镜的和传统的开放式远端胃切除术以及D2淋巴结切除术治疗晚期胃癌的效果和安全性。
 

在2012年9月到2014年12月期间，共有1056名临床T2-4An0-3m0期胃癌患者参与了此项研究。受试者被随机均分为两组，每组528人，其中一组接受腹腔镜远端胃部切除术和淋巴结切除术，另一组接受开放式胃切除术和D2淋巴结切除术。来自中国14家医院的15名经验丰富的医生进行了此项试验。在意向性治疗分析原则的基础上，比较手术后三十天内两组间死亡率和发病率的差异。术后并发症是根据Clavien-Dindo分类法进行分级的。两组的D2淋巴结切除术服从率很接近。手术后，腹腔镜切除术组的发病率为15.2%，而另一组则为12.9%，二者并没有显著性差异。两组的死亡率分别为0.4%和0。两组间的严重性的分布也很类似。
 
通过此次研究，我们可以发现对于经验丰富的医生来说，进行腹腔镜远端胃部切除术以及D2淋巴切除术治疗晚期胃癌是安全的。

原始出处：

Yanfeng Hu et al. Morbidity and Mortality of Laparoscopic Versus Open D2 Distal Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial. JCO. Published Ahead of Print on February 22, 2016 as 10.1200/JCO.2015.63.7215

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    2017-01-29 doctorzheng

    #切除术#

    0

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    2016-08-03 lidong40

    #JCO#

    0

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    2016-03-02 xinxin088

    #腹腔镜#

    0

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    2016-03-02 bshuang

    #胃切除#

    0

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    2016-03-02 changhe718

    #研究团队#

    0

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