Hepatology:哪种肾脏替代方式与急性肝衰竭的血氨水平和死亡率降低有关?

2017-09-02 MedSci MedSci原创

高血氨症与急性肝衰竭(ALF)患者的颅内高血压和死亡率有关。近期,一项发表在杂志Hepatology上的研究评估了肾脏替代疗法(RRT)对ALF患者血清氨的水平和结局的影响。此项研究为来自美国 1998/01-2016/12的ALF研究组注册表的连续ALF患者的多中心队列研究。首先,研究者们评估了血氨与肝性脑病(HE)和21天无移植生存(TFS)(n = 1186)之间的关系。其次,研究了RRT对

高血氨症与急性肝衰竭(ALF)患者的颅内高血压和死亡率有关。近期,一项发表在杂志Hepatology上的研究评估了肾脏替代疗法(RRT)对ALF患者血清氨的水平和结局的影响。此项研究为来自美国 1998/01-2016/12的ALF研究组注册表的连续ALF患者的多中心队列研究。首先,研究者们评估了血氨与肝性脑病(HE)和21天无移植生存(TFS)(n = 1186)之间的关系。其次,研究了RRT对入院后前3天(n = 340)的血氨水平和21天TFS(n = 1186)的影响。此项研究结果显示:由于神经系统(181 vs. 90μmol/l)和所有原因(114 vs. 83μmol/L),较高的入院(n = 1186)中位氨水平与3-4级HE(116 vs. 83μmol/ l;P <0.001)和第21天的死亡率相关。在340例连续检测血氨水平的患者中,61例(18%)为连续RRT(CRRT),59例(17%)为间歇性RRT(IRRT),220例(65%)在前2天无RRT。从第1天到第3天,中位氨在CRRT,IRRT和无RRT组患者中分别下降了38%,23%和19%。相对于无R

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    2017-09-07 1e1263e3m20(暂无匿称)

    学习了多谢分享

    0

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    2017-09-06 1e10c84am36(暂无匿称)

    文章很好.赞赞赞

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1635785, encodeId=0ac71635e85ef, content=<a href='/topic/show?id=9e5781499dd' target=_blank style='color:#2F92EE;'>#肝衰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81499, encryptionId=9e5781499dd, topicName=肝衰)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fedc22527786, createdName=1249884fm94暂无昵称, createdTime=Sat Jun 23 04:48:00 CST 2018, time=2018-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241381, encodeId=028824138134, content=学习了多谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Thu Sep 07 08:27:39 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=240957, encodeId=c25d24095e82, content=文章很好.赞赞赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 06 07:28:27 CST 2017, time=2017-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290466, encodeId=57801290466e6, content=<a href='/topic/show?id=fb34523817d' target=_blank style='color:#2F92EE;'>#急性肝衰竭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52381, encryptionId=fb34523817d, topicName=急性肝衰竭)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f54230, createdName=xlysu, createdTime=Mon Sep 04 06:48:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426817, encodeId=b65c142681ec7, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Mon Sep 04 06:48:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=240060, encodeId=11c724006065, content=继续学习中谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Sun Sep 03 15:48:57 CST 2017, time=2017-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=240059, encodeId=4e5524005959, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Sun Sep 03 15:48:52 CST 2017, time=2017-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239821, encodeId=0ee623982162, content=学习了不少事情!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4BGdu4COj6QWFqgMd3xnWDdgLZKUGI32veZvO2qFAQvpYr1eMbUOTqMvlZWc3MsugtFMHzxDwial/0, createdBy=88731939304, createdName=圣艮山, createdTime=Sat Sep 02 21:51:50 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239800, encodeId=cc63239800cd, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Sep 02 19:40:52 CST 2017, time=2017-09-02, status=1, ipAttribution=)]
    2017-09-04 gwc384
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    2017-09-03 往日如昨

    继续学习中谢谢

    0

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    2017-09-03 往日如昨

    学习了谢谢分享

    0

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    2017-09-02 圣艮山

    学习了不少事情!

    0

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    2017-09-02 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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