多发性硬化症与脑小血管病的鉴别诊断

2022-06-24 张忠玲 MedSci原创

哈尔滨医科大学第一附属医院

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    2022-09-26 jml2009
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该研究发现,多发性硬化症患者骨髓内的 T 细胞克隆数量和多样性明显增加。 

JNNP:多发性硬化发病时,患者的年龄在往后推移

多发性硬化症(MS)的发病年龄从儿童期一直到成年期,尽管大多数患者在20-30岁时首次出现脱髓鞘事件。MS早发,也称为儿科或青少年MS,定义为16-18岁之前发生第一次临床脱髓鞘事件,约占所有MS病例

JNNP:生酮饮食治疗复发性多发性硬化症的II期研究,安全性、耐受性和潜在临床益处

多发性硬化(MS)受遗传和环境因素的影响。饮食摄入影响免疫状况和功能,包括宿主免疫系统的发育、对病原体的保护和免疫反应的维持。因此,研究人员将饮食调整作为影响免疫介导疾病(如MS)的一种方式。生酮饮食

FDA批准用于多发性硬化的外骨骼机器人

6月13日,Ekso Bionics公司宣布其外骨骼机器人设备EksoNR获得美国FDA批准,可用于有行走困难的多发性硬化(MS)患者的康复。这是FDA批准的首个用于MS患者康复的外骨骼机器人。

JNNP:既往疾病改良治疗对AHSCT治疗MS患者安全性和疗效的影响

体造血干细胞移植(AHSCT)是侵袭性复发缓解型多发性硬化(RRMS)患者的一种治疗选择。治疗的基本原理是给予免疫消融治疗,导致自身反应细胞的耗尽,然后输注冷冻保存的自体造血干细胞以支持免疫重建。&n

Cell:天津医大学者证实骨髓免疫可能是多发性硬化症的关键

通过再平衡骨髓造血系统,回归免疫系统稳态,减轻神经系统炎症损伤。