Hypertension:顽固性高血压增心血管病和终末期肾病风险

2014-08-21 高晓方 译 医学论坛网

美国一项研究表明,显著顽固性高血压(aTRH)可升高心血管疾病和终末期肾病风险。论文8月4日在线发表于《高血压》(Hypertension)。 此项研究从14684例接受降压治疗的受试者中确定了1870例aTRH患者,并评估了aTRH与冠心病、卒中、全因死亡、心衰、外周动脉疾病和终末期肾病的相关性。应用利尿剂并非aTRH所必需。 结果显示,与无aTRH的受试者相比,aTRH患者的冠

美国一项研究表明,显著顽固性高血压(aTRH)可升高心血管疾病和终末期肾病风险。论文8月4日在线发表于《高血压》(Hypertension)。

此项研究从14684例接受降压治疗的受试者中确定了1870例aTRH患者,并评估了aTRH与冠心病、卒中、全因死亡、心衰、外周动脉疾病和终末期肾病的相关性。应用利尿剂并非aTRH所必需。

结果显示,与无aTRH的受试者相比,aTRH患者的冠心病、卒中、全因死亡、心衰、外周动脉疾病和终末期肾病的多变量校正危险比(HR)分别为1.44、1.57、1.30、1.88、1.23和1.95。aTRH与冠心病和心血管疾病综合转归(HR 1.47和1.46)亦有相关性。

原始出处:

Paul Muntner, Barry R. Davis, William C. Cushman, Sripal Bangalore, David A. Calhoun, Sara L. Pressel, Henry R. Black, John B. Kostis, Jeffrey L. Probstfield, Paul K. Whelton, Mahboob Rahman, for the ALLHAT Collaborative Research Group*Treatment-Resistant Hypertension and the Incidence of Cardiovascular Disease and End-Stage Renal Disease.Results From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)HYPERTENSIONAHA.114.03850


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    2014-09-11 feather89
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