JACC:血管内超声对冠心病的诊断预测价值研究

2018-10-19 MedSci MedSci原创

既往研究表明,血管内超声(IVUS)和射频(RF)-IVUS可以检测高风险的冠脉斑块。本研究的目的旨在评估RF-IVUS在冠心病(CAD)患者中的应用价值。本研究纳入了2008-2011年581名行冠脉造影的冠心病或稳定性心绞痛患者,并通过RF-IVUS对其一条非狭窄的冠脉进行检测评估。主要终点事件是主要心血管不良事件(MACE)。经过平均4.7年时间的随访,152名(26.2%)患者出现MACE

既往研究表明,血管内超声(IVUS)和射频(RF)-IVUS可以检测高风险的冠脉斑块。本研究的目的旨在评估RF-IVUS在冠心病(CAD)患者中的应用价值。

本研究纳入了2008-2011年581名行冠脉造影的冠心病或稳定性心绞痛患者,并通过RF-IVUS对其一条非狭窄的冠脉进行检测评估。主要终点事件是主要血管不良事件(MACE)。经过平均4.7年时间的随访,152名(26.2%)患者出现MACE,存在管腔面积≤4.0 mm2与MACE呈独立相关性(HR: 1.49; 95% CI: 1.07 - 2.08; p = 0.020),存在斑块负担≥70%与心源性死亡、非致死性冠脉综合征和意外的血运重建的复合终点事件呈独立相关(HR: 1.66; 95% CI: 1.06 - 2.58; p = 0.026)。另外,斑块负担每增加10-U,复合终点事件的发生风险就增加26%((HR: 1.26; 95% CI: 1.03 - 1.52; p = 0.022)。

研究结果显示,在冠心病患者中,血管内超声提示的管腔面积狭小和斑块负担过重对患者的主要心血管不良事件的发生有提示作用。

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    2019-03-22 hbwxf
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    2018-10-19 changjiu

    谢谢分享,学习一下谢谢

    0

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