Diabetic Med:膳食蛋白质影响1型糖尿病患者餐后血糖正常所需的胰岛素输送剂量和模式

2019-05-08 不详 网络

近日,国际杂志 《Diabetic Med》上在线发表一项关于膳食蛋白质影响1型糖尿病患者餐后血糖正常所需的胰岛素输送剂量和模式的随机试验的研究。 mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:major-fareast; color:black;mso-bidi-font-weight:bold">近日,国际

近日,国际杂志 《Diabetic Med》上在线发表一项关于膳食蛋白质影响1糖尿病患者餐后血糖正常所需的胰岛素输送剂量和模式的随机试验的研究。

在这项交叉研究中,患有1糖尿病的年轻人被随机分为高剂量(60克)或低蛋白质膳食(5克),每人含有30克碳水化合物和8克脂肪。使用胰岛素钳技术的变体来确定在接下来的5小时内维持血糖正常的胰岛素需求。

总共11名参与者(平均值± sd年龄16.5±2.7岁,HbA 1c 52±8.7 mmol / mol [6.9±0.8]糖尿病病程6.9±5.1年)完成了该研究。高蛋白饮食的平均胰岛素需求量高于低蛋白饮食[10.3CI 8.2,12.57 VS 6.7单位(CI 4.7,8.8; P = 0.001],是个体间低蛋白质膳食要求的0.96倍。在前2小时给予大约一半的额外胰岛素[1.1单位/小时(CI 0.5,1.8; P = 0.001],相比之下,第二个2小时消耗额外的0.5单位/小时(CI -0.2,1.2; P = 0.148),在最后一小时内消耗0.1个单位(CI -0.6,0.8; P = 0.769)。

高蛋白质膳食比含有相同数量碳水化合物的低蛋白质膳食需要多50%的胰岛素来维持正常血糖。大多数是在前2小时内需要的。膳食蛋白质的胰岛素需求存在个体差异。

原始出处:

M. EvansC. E. M. SmartN. Paramalingamet al. Dietary protein affects both the dose and pattern of insulin delivery required to achieve postprandial euglycaemia in Type 1 diabetes: a randomized trial

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    2019-09-21 baoya
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    2019-09-28 QFXL123456

    学习了

    0

  5. 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  6. 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  7. 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近日,国际杂志 《Diabetic Med》上在线发表一项关于儿科糖尿病生活质量量表(PedsQL)3.2模块对2型糖尿病青少年的信度和效度的研究。