JACC:搭桥术后新发房颤的发生风险更大,预后更差

2018-02-23 MedSci MedSci原创

经皮冠脉介入术(PCI)后和冠脉搭桥术(CABG)后的冠脉左主干病变(LMCAD)患者发生新发房颤的风险尚属未知。本研究的目的旨在评估PCI和CABG术后的左主干病变患者发生新发房颤的发病率和3年预后。本EXCEL临床试验纳入了1905名LMCAD患者,并将其随机分成PCI组和CABG组,随访观察其临床预后。在1812名无房颤的手术患者中,有162名(8.9%)患者在血运重建后2.7 ± 2.5天

经皮冠脉介入术(PCI)后和冠脉搭桥术(CABG)后的冠脉左主干病变(LMCAD)患者发生新发房颤的风险尚属未知。本研究的目的旨在评估PCI和CABG术后的左主干病变患者发生新发房颤的发病率和3年预后。本EXCEL临床试验纳入了1905名LMCAD患者,并将其随机分成PCI组和CABG组,随访观察其临床预后。在1812名无房颤的手术患者中,有162名(8.9%)患者在血运重建后2.7 ± 2.5天出现了新发房颤,包括161名CABG组和1名PCI组的患者(p < 0.0001)。在CABG组患者中,高龄、高的BMI指数和低的左室射血分数是新发房颤的独立危险因素。与无新发房颤患者相比,有新发房颤的患者住院时间要更长,服用抗凝剂的几率更大,出血的概率也更大(14.2% vs. 5.5%; p < 0.0001)。多变量分析后,CABG后的新发房颤是术后3年卒中发生、死亡、心梗的独立预测因子。研究结果显示,冠脉搭桥术后的新发房颤较常见,PCI术后很罕见,并且新发房颤与患者远期的卒中和死亡风险明显相关。原始出处:Ioanna K et al.New-Onset Atrial Fib

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createdName=12498568m50暂无昵称, createdTime=Sun Feb 25 13:12:00 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2019-01-22 hbwxf
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    2018-05-02 jyzxjiangqin

    搭桥术后新发房颤风险更大.

    0

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createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Mar 28 07:16:34 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296687, encodeId=402b29668eb7, content=搭桥术后新发房颤., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Mar 16 07:14:24 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293770, encodeId=3e3b293e7092, content=学习了.不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:22:48 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292431, encodeId=fb3c292431a4, content=搭桥术后新发房颤风险大., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Mar 03 06:42:19 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325711, encodeId=368b1325e11dc, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Feb 25 13:12:00 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-04-22 jyzxjiangqin

    搭桥术后新发房颤风险.

    0

  5. 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createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Apr 22 07:30:06 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=304402, encodeId=285030440234, content=搭桥术后新发房颤风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Tue Apr 10 07:22:04 CST 2018, time=2018-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300439, encodeId=487d300439fc, content=搭桥术后新发房颤., beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Mar 28 07:16:34 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296687, encodeId=402b29668eb7, content=搭桥术后新发房颤., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Mar 16 07:14:24 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293770, encodeId=3e3b293e7092, content=学习了.不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:22:48 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292431, encodeId=fb3c292431a4, content=搭桥术后新发房颤风险大., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Mar 03 06:42:19 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325711, encodeId=368b1325e11dc, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Feb 25 13:12:00 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-04-10 jyzxjiangqin

    搭桥术后新发房颤风险.

    0

  6. 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createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Mar 28 07:16:34 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296687, encodeId=402b29668eb7, content=搭桥术后新发房颤., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Mar 16 07:14:24 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293770, encodeId=3e3b293e7092, content=学习了.不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:22:48 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292431, encodeId=fb3c292431a4, content=搭桥术后新发房颤风险大., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Mar 03 06:42:19 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325711, encodeId=368b1325e11dc, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Feb 25 13:12:00 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-03-28 jyzxjiangqin

    搭桥术后新发房颤.

    0

  7. 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createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Mar 28 07:16:34 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296687, encodeId=402b29668eb7, content=搭桥术后新发房颤., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Mar 16 07:14:24 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293770, encodeId=3e3b293e7092, content=学习了.不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Wed Mar 07 07:22:48 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292431, encodeId=fb3c292431a4, content=搭桥术后新发房颤风险大., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Mar 03 06:42:19 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325711, encodeId=368b1325e11dc, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Feb 25 13:12:00 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-03-16 jyzxjiangqin

    搭桥术后新发房颤.

    0

  8. 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CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292431, encodeId=fb3c292431a4, content=搭桥术后新发房颤风险大., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Mar 03 06:42:19 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325711, encodeId=368b1325e11dc, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Feb 25 13:12:00 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-03-07 owlhealth

    学习了.不错耶

    0

  9. 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CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292431, encodeId=fb3c292431a4, content=搭桥术后新发房颤风险大., beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Mar 03 06:42:19 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325711, encodeId=368b1325e11dc, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Feb 25 13:12:00 CST 2018, time=2018-02-25, status=1, ipAttribution=)]
    2018-03-03 jyzxjiangqin

    搭桥术后新发房颤风险大.

    0

  10. 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