Circulation:窦性心律传导异常点指导的室速的靶向消融

2019-10-24 梅梅 梅斯原创

准确和快速的识别最容易再起搏的瘢痕区域是指导室性心动过速(,简称室速,VT)射频消融的必要条件。研究人员前瞻性评估了窦性心律时,靶向心室激动传导分析所鉴定的减速带(DZ)进行的VT射频消融的预后。本研究招募了120位瘢痕相关的室速患者(中位年龄65岁[59-71],15%的女性,50%的非缺血性,中位射血分数为31%),共进行了144次射频消融。57%的患者既往进行过射频消融,59%的患者有心外膜

准确和快速的识别最容易再起搏的瘢痕区域是指导室性心动过速(,简称室速,VT)射频消融的必要条件。研究人员前瞻性评估了窦性心律时,靶向心室激动传导分析所鉴定的减速带(DZ)进行的VT射频消融的预后。

本研究招募了120位瘢痕相关的室速患者(中位年龄65岁[59-71],15%的女性,50%的非缺血性,中位射血分数为31%),共进行了144次射频消融。57%的患者既往进行过射频消融,59%的患者有心外膜接触史。

在基线心律期间进行了高密度绘图(心内膜 2518个点[1615-3752],心外膜 5049±2580个点),最后,每位患者确定了2±1个减速带,95%的患者的减速带与成功终止室速的点相同。靶向DZ的中位总射频时间为29min(21-38min)。12±10个月时,70%的患者未复发室速。总体存活率为87%。

一种新型的不依赖电压的高密度绘图显示器可在窦性心律中识别窦性心动过速的功能位点,并指导靶向射频消融,从而避免了广泛的射频消融的需要。基线节律时,传导拥堵的区域是预测的VT终止位点,为减速带是高度致心律失常、可作异位起搏点的推论提供了机制证据。

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