JAHA:不同手术方式对主动脉缩窄患者预后的影响

2019-04-03 不详 MedSci原创

主动脉缩窄(COA)即使接受了合适的治疗也会发生血管功能不全,但COA的治疗方法对血管功能的影响尚不清楚。本研究的目的旨在评估和比较外科手术、球囊扩张(BD)和支架植入治疗COA对血管功能的影响。本研究纳入了75例COA患者(28例为外科手术,23例为BD,24例支架植入),患者入组时的年龄、COA严重程度、压差梯度和代谢水平相似,但接受治疗时的年龄不尽相同。系统性高血压、主动脉僵硬度、内皮功能和

主动脉缩窄(COA)即使接受了合适的治疗也会发生血管功能不全,但COA的治疗方法对血管功能的影响尚不清楚。本研究的目的旨在评估和比较外科手术、球囊扩张(BD)和支架植入治疗COA对血管功能的影响。

本研究纳入了75例COA患者(28例为外科手术,23例为BD,24例支架植入),患者入组时的年龄、COA严重程度、压差梯度和代谢水平相似,但接受治疗时的年龄不尽相同。系统性高血压、主动脉僵硬度、内皮功能和左心室质量的患病率在各组间无明显差异,然而,BD组患者的升主动脉扩张水平更高,运动时收缩压峰值更低,日血压变化受损更小,炎症生物标志物更低。

研究结果显示,对于主动脉缩窄患者,治疗方式对主要血管预后无明显影响,球囊扩张治疗在有些指标预后中更佳。

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    2019-04-05 zhaohui6731
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    2019-04-03 329523732

    不错

    0

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