Crit Care Med:小儿创伤后急性呼吸窘迫综合征的危险因素

2018-09-08 xing.T MedSci原创

由此可见,该研究首次描述了小儿创伤患者急性呼吸窘迫综合征的发生率和危险因素。在儿科创伤后更好地了解与急性呼吸窘迫综合征相关的危险因素可能有助于医务人员预测其发展并尽早干预以改善严重受伤儿童的预后。

近日,危重病医学领域权威杂志Critical Care Medicine上发表了一篇研究文章,研究人员旨在明确重症患儿中与急性呼吸窘迫综合征发展相关的入院时可识别的危险因素。

该研究为一项回顾性队列研究,从2007年到2016年期间,研究人员以患有创伤性损伤的未满18岁的ICU患者为研究对象,并确定了患者、损伤和临床特征之间的关联,这些特征与医院并发症记录的急性呼吸窘迫综合征的发展有关。

146058名重伤儿童中1.8%(n=2590)的患者发生急性呼吸窘迫综合征。在多变量分析中,与发生急性呼吸窘迫综合征的风险较高相关的唯一人口统计学因素是非裔美国人种族(与白人相比相对风险为1.42; 95%CI为1.13-1.78)。创伤的特征包括火器伤(相对风险为1.93; 1.50-2.48)和机动车碰撞(相对风险为1.91; 1.57-2.31),相比于跌倒; 脊柱(相对风险为1.39; 1.20-1.60),胸部(相对风险为1.36; 1.22-1.52)或下肢损伤(相对风险为1.26; 1.10-1.44); 截肢(相对风险为2.10; 1.51-2.91)和更严重的创伤(伤害严重程度得分为40-75与1-8相比相对风险为3.69,2.58-5.44)。临床变量包括异常呼吸状态(插管相对风险为1.67; 1.23-2.26和呼吸不足相对风险为1.23; 1.05-1.45和呼吸急促相对风险为1.26; 1.10-1.44)以及较低的格拉斯哥昏迷量表评分(格拉斯哥昏迷量表得分3与15相比的相对风险为5.61,4.44-7.07)。

由此可见,该研究首次描述了小儿创伤患者急性呼吸窘迫综合征的发生率和危险因素。在儿科创伤后更好地了解与急性呼吸窘迫综合征相关的危险因素可能有助于医务人员预测其发展并尽早干预以改善严重受伤儿童的预后。

原始出处:

Killien, Elizabeth Y,et al. Risk Factors on Hospital Arrival for Acute Respiratory Distress Syndrome Following Pediatric Trauma.critical care medicine.2018. https://journals.lww.com/ccmjournal/Abstract/onlinefirst/Risk_Factors_on_Hospital_Arrival_for_Acute.96170.aspx

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    2018-10-10 suncunjie1981

    f学习一下

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    2018-09-22 13718711b3m

    值得学习与借鉴的临床经验,涨知识!受益匪浅,感谢分享!

    0

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    2018-09-10 易水河

    学习学习

    0

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    2018-09-08 ylzr123

    认真学习,不断进步,把经验分享给同好。点赞了!

    0