SCI REP:CHADS2和CHA2DS2-VASc评分对房颤患者急性心肌梗死的预测价值!

2017-07-05 xing.T MedSci原创

由此可见,CHA2DS2-VASc评分具有很好的识别高危房颤患者的预测价值,但是在预测发生急性心肌梗死的患者上其并不显著优于CHADS2评分。

急性心肌梗死(AMI)导致心房颤动(房颤)预后不良,与患者死亡率显著增加有关。日,Scientific reports 杂志上发表了一篇研究文章,该研究旨在探讨CHADS2和CHA2DS2-VASc评分对房颤患者急性心肌梗死的预测价值。

这项回顾性研究纳入了5140例非瓣膜性房颤患者,300例急性心肌梗死患者和4840例无急性心肌梗死的受试者。研究人员旨在基于预测急性心肌梗死风险的接受者操作特征曲线来确定CHADS2和CHA2DS2-VASc评分的最佳截断值。

研究人员发现CHADS2评分和CHA2DS2-VASc评分与房颤患者发生急性心肌梗死的比值比增高相关,在对高脂血症、高尿酸血症、甲状腺功能亢进、甲状腺功能减退症和阻塞性睡眠呼吸暂停进行调整后。

目前该研究的结果表明,在预测高危急性心肌梗死的房颤患者上CHADS2评分曲线下面积(AUC)为0.787,CHA2DS2-VASc评分具有相似的准确性(AUC为0.750)。然而,这两个基于临床的风险评分的预测准确性相似。

由此可见,CHA2DS2-VASc评分具有很好的识别高危房颤患者的预测价值,但是在预测发生急性心肌梗死的患者上其并不显著优于CHADS2评分。

原始出处:

Hui Pang,et al. Predictive value of CHADS2 and CHA2DS2-VASc scores for acute myocardial infarction in patients with atrial fibrillation.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-04604-w

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    2017-08-22 quxin068
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    2017-08-04 huperzia
  4. 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  5. 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  6. 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  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jul 05 20:29:47 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218915, encodeId=4a4921891525, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Wed Jul 05 20:29:18 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-06 maymoon1983

    可是vas的评分推荐用抗凝的比之前评分多好多呢

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jul 05 20:29:47 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218915, encodeId=4a4921891525, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Wed Jul 05 20:29:18 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-05 changjiu

    学习了,谢谢

    0

  10. 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createdTime=Fri Jul 07 10:20:00 CST 2017, time=2017-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=219065, encodeId=71de219065ba, content=可是vas的评分推荐用抗凝的比之前评分多好多呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0iaeHUsbIzwsociaXY4eY8DryoMrt2gEdB9WBJl32NBRdY2JLRtDPibf3KoIM53fldicMJYbSUWVaXU/0, createdBy=e6fc75818, createdName=maymoon1983, createdTime=Thu Jul 06 07:49:44 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218918, encodeId=b96221891859, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jul 05 20:29:47 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218915, encodeId=4a4921891525, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Wed Jul 05 20:29:18 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-05 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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