CHMP对Mylan和Fujifilm的阿达木单抗生物类似物Hulio持积极态度

2018-07-29 MedSci MedSci原创

Mylan和Fujifilm生物制药公司近日宣布,欧洲药品管理局的人用药品委员会(CHMP)对Hulio的营销授权申请持积极的意见,Hulio为Humira(adalimumab,阿达木单抗)的生物类似物,适用于阿达木单抗的所有适应症。

类风湿关节炎 (RA) 是一种以对称性、多关节、小关节为主的慢性自身免疫性疾病,素有不死癌症之称,患病者的免疫系统会破坏健康关节,引发关节疼痛、肿胀、僵硬,产生疲劳和无力的症状,晚期可强直和畸形、功能严重受损,并最终导致关节功能丧失。阿达木单抗已经成为RA治疗的先进生物靶向性药物。

MylanFujifilm生物制药公司近日宣布,欧洲药品管理局的人用药品委员会(CHMP)对Hulio的营销授权申请持积极的意见,HulioHumiraadalimumab,阿达木单抗)的生物类似物,适用于阿达木单抗的所有适应症。

Mylan首席执行官Heather Bresch评论说:我们迫切需要为患有类风湿性关节炎、斑块状银屑病和克罗恩病等慢性炎症的患者提供更实惠的治疗选择。CHMP的决定基于Hulioadalimumab生物相似结果,代表了向患者提供这种治疗的积极步骤Fujifilm总裁兼首席执行官Yoshifumi Torii博士说:我们将继续致力于提供高质量的生物仿制药,并强烈希望Hulio为整个欧洲国家的患者提供巨大的价值Mylan总裁Rajiv Malik补充道:“Mylan非常自豪能成为欧洲第一波阿达木单抗生物仿制药的制造商之一。我们将继续在全球市场寻找机会,为患者增加治疗选择,并尽量减少医疗成本负担


原始出处:

http://www.firstwordpharma.com/node/1581494?tsid=4#axzz5MVjkDWbV

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    2018-10-12 haouestc
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    2018-11-27 JR19860219
  4. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97945, encryptionId=3eb39e945b2, topicName=阿达木)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3dba19658752, createdName=1179102698_36768932, createdTime=Tue Jul 31 12:33:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335076, encodeId=65d23350e681, content=了解一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Mon Jul 30 08:47:16 CST 2018, time=2018-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335017, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jul 29 23:02:42 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-31 医生2394
  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jul 29 23:02:42 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-31 waiwai3036
  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jul 29 23:02:42 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
  7. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jul 29 23:02:42 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-30 kafei

    了解一下谢谢

    0

  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jul 29 23:02:42 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-30 飛歌

    学习了很有用不错

    0

  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jul 29 23:02:42 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-29 phoebeyan520

    学习了学习了我,谢谢

    0

  10. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jul 29 23:02:42 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-29 清风拂面

    谢谢分享学习

    0