Nature Human Behaviour:睡眠,焦虑,Nature子刊证实两者间强大大的神经联系

2019-11-05 佚名 中国生物技术网

你感到焦虑吗?昨晚你睡好了吗?当谈到管理焦虑症时,就像莎士比亚笔下的麦克白所说的:睡眠是“受伤心灵的慰藉”。11月5日,发表在《Nature Human Behaviour》上的一项新研究显示,整晚的睡眠可以稳定情绪,而不眠之夜可能会引发焦虑水平上升30%。该研究由美国加州大学伯克利分校Matthew Walker教授领导,它提供了迄今为止在睡眠和焦虑之间最强大的神经联系之一。

你感到焦虑吗?昨晚你睡好了吗?当谈到管理焦虑症时,就像莎士比亚笔下的麦克白所说的:睡眠是“受伤心灵的慰藉”。11月5日,发表在《Nature Human Behaviour》上的一项新研究显示,整晚的睡眠可以稳定情绪,而不眠之夜可能会引发焦虑水平上升30%。该研究由美国加州大学伯克利分校Matthew Walker教授领导,它提供了迄今为止在睡眠和焦虑之间最强大的神经联系之一。

研究人员发现,最容易让焦虑大脑平静下来的睡眠类型是深度睡眠,也称为非快速眼动(NREM)慢波睡眠。在这种状态下,神经振荡变得高度同步,心率和血压也会下降。

研究通讯作者、神经科学和心理学教授Matthew Walker说:“我们已经发现了深度睡眠的一种新功能,它可以通过重组大脑的连接,在一夜之间减少焦虑。深度睡眠似乎是一种天然的焦虑抑制剂,只要我们每天晚上都能这样做。”

研究人员还指出,睡眠是一种自然且非药物治疗焦虑症的手段。

今年年初,《柳叶刀·精神病学》发表的北京大学第六医院牵头的中国首次全国性精神障碍流行病学调查显示,我国精神障碍疾病(不含老年期痴呆)患病率为9.32%,焦虑障碍患病率最高为4.98%,且随着我国社会心理和人口学因素发生的巨大变化,诸多因素导致的焦虑障碍的患病率呈上升趋势,越来越多的人群正在饱受焦虑症的困扰。

研究第一作者、人类睡眠科学中心的博士后研究员Eti Ben Simon说:“我们的研究有力地表明,睡眠不足会加剧焦虑。相反,深度睡眠有助于减轻这种压力。”

在使用功能性磁共振成像(MRI)和多导睡眠描记术的一系列实验中,研究人员扫描了18名年轻人的大脑。他们在经历整晚睡眠后和通宵不眠后观看了激动人心的视频片段。焦虑水平是通过一份名为“状态-特质焦虑量表”的问卷在每次治疗后测量的。

经过一个不眠夜后,大脑扫描显示内侧前额叶皮层关闭。这通常有助于控制我们的焦虑,而大脑更深的情感中心过于活跃。

研究表明,一个不眠夜可以使焦虑水平提高30%。图片来源:Eti Ben Simon

Walker说:“如果没有睡眠,就好像大脑的情感油门踩得太重,却没有足够的刹车。”

研究人员通过放置在参与者头上的电极测量他们的脑电波,结果显他们的焦虑水平明显下降,尤其是对于那些经历了NREM慢波睡眠的人。

Simon说:“深度睡眠已经恢复了大脑的前额叶调节机制,该机制调节我们的情绪,降低了情绪和生理反应能力,并防止了焦虑升级。”

除了测量18名原始研究参与者的睡眠-焦虑关系外,研究人员在另外30名参与者的研究中复制了这一结果。在所有参与者中,结果再次显示,那些晚上睡眠程度更深的人第二天的焦虑水平最低。

此外,除了实验室实验,研究人员还进行了一项在线研究。他们跟踪了280名不同年龄的人在连续四天内睡眠和焦虑水平的变化。结果显示,参与者从第一晚到第二晚的睡眠时间和质量可以预测他们次日的焦虑程度。即使是夜间睡眠的细微变化也会影响他们的焦虑水平。

Simon说:“患有焦虑症的人经常报告睡眠受到干扰,但睡眠改善很少被认为是降低焦虑的临床建议。我们的研究不仅确定了睡眠和焦虑之间的因果关系,还确定了我们需要哪种深度非快速眼动睡眠来安抚过度焦虑的大脑。”

Walker说:“在社会层面上,大多数工业化国家中,睡眠时间的减少和这些国家中焦虑症的显着增加可能不是巧合,而是因果相关的。在绝望和希望之间最好的桥梁就是睡个好觉。”

原始出处:
Eti Ben Simon, Aubrey Rossi, Allison G. Harvey ,et al.Overanxious and underslept.Nature Human Behaviour .Published: 04 November 2019

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    2020-06-14 liye789132251
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    2020-09-08 tamgche
  4. [GetPortalCommentsPageByObjectIdResponse(id=1947890, encodeId=e35b194e89088, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 13 12:24:00 CST 2019, time=2019-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883973, encodeId=eebd18839e3b5, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Jun 14 17:24:00 CST 2020, time=2020-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940437, encodeId=5aed194043efe, content=<a href='/topic/show?id=0de4919efc' target=_blank style='color:#2F92EE;'>#human#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9197, encryptionId=0de4919efc, topicName=human)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Tue Sep 08 01:24:00 CST 2020, time=2020-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970239, encodeId=954319e0239dc, content=<a href='/topic/show?id=d889e449683' target=_blank style='color:#2F92EE;'>#神经联系#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74496, encryptionId=d889e449683, topicName=神经联系)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6595338, createdName=xuruicheng, createdTime=Thu Dec 19 19:24:00 CST 2019, time=2019-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1521943, encodeId=dca8152194302, content=<a href='/topic/show?id=f83866137f' target=_blank style='color:#2F92EE;'>#EHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6613, encryptionId=f83866137f, topicName=EHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937d11405368, createdName=qjddjq, createdTime=Thu Nov 07 04:24:00 CST 2019, time=2019-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=374825, encodeId=cdda3e482515, content=所以要调睡眠, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0225163045, createdName=146bea4cm28暂无昵称, createdTime=Tue Nov 05 19:24:18 CST 2019, time=2019-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=374823, encodeId=2c313e482321, content=可是焦虑就会睡不着,睡不好第二天会更焦虑 ,这不是恶性循环了吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLpFkye0MszfOIta2ICWOuagHxYneO5ibUMnoQ3chbt7QlevhbuytsickjZib2T6Rox9vCftFB4codXg/132, createdBy=8ab15083450, createdName=Korsean, createdTime=Tue Nov 05 17:32:57 CST 2019, time=2019-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050508, encodeId=f90b10505089e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Tue Nov 05 16:24:00 CST 2019, time=2019-11-05, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1947890, encodeId=e35b194e89088, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 13 12:24:00 CST 2019, time=2019-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883973, encodeId=eebd18839e3b5, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Jun 14 17:24:00 CST 2020, time=2020-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940437, encodeId=5aed194043efe, content=<a href='/topic/show?id=0de4919efc' target=_blank style='color:#2F92EE;'>#human#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9197, encryptionId=0de4919efc, topicName=human)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Tue Sep 08 01:24:00 CST 2020, time=2020-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970239, encodeId=954319e0239dc, content=<a href='/topic/show?id=d889e449683' target=_blank style='color:#2F92EE;'>#神经联系#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74496, encryptionId=d889e449683, topicName=神经联系)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6595338, createdName=xuruicheng, createdTime=Thu Dec 19 19:24:00 CST 2019, time=2019-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1521943, encodeId=dca8152194302, content=<a href='/topic/show?id=f83866137f' target=_blank style='color:#2F92EE;'>#EHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6613, encryptionId=f83866137f, topicName=EHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937d11405368, createdName=qjddjq, createdTime=Thu Nov 07 04:24:00 CST 2019, time=2019-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=374825, encodeId=cdda3e482515, content=所以要调睡眠, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0225163045, createdName=146bea4cm28暂无昵称, createdTime=Tue Nov 05 19:24:18 CST 2019, time=2019-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=374823, encodeId=2c313e482321, content=可是焦虑就会睡不着,睡不好第二天会更焦虑 ,这不是恶性循环了吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLpFkye0MszfOIta2ICWOuagHxYneO5ibUMnoQ3chbt7QlevhbuytsickjZib2T6Rox9vCftFB4codXg/132, createdBy=8ab15083450, createdName=Korsean, createdTime=Tue Nov 05 17:32:57 CST 2019, time=2019-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050508, encodeId=f90b10505089e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Tue Nov 05 16:24:00 CST 2019, time=2019-11-05, status=1, ipAttribution=)]
    2019-11-07 qjddjq
  6. [GetPortalCommentsPageByObjectIdResponse(id=1947890, encodeId=e35b194e89088, content=<a href='/topic/show?id=e54d8483db' target=_blank style='color:#2F92EE;'>#HAV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8483, encryptionId=e54d8483db, topicName=HAV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Fri Dec 13 12:24:00 CST 2019, time=2019-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883973, encodeId=eebd18839e3b5, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Jun 14 17:24:00 CST 2020, time=2020-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1940437, encodeId=5aed194043efe, content=<a href='/topic/show?id=0de4919efc' target=_blank style='color:#2F92EE;'>#human#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9197, encryptionId=0de4919efc, topicName=human)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Tue Sep 08 01:24:00 CST 2020, time=2020-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970239, encodeId=954319e0239dc, content=<a href='/topic/show?id=d889e449683' target=_blank style='color:#2F92EE;'>#神经联系#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74496, encryptionId=d889e449683, topicName=神经联系)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6595338, createdName=xuruicheng, createdTime=Thu Dec 19 19:24:00 CST 2019, time=2019-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1521943, encodeId=dca8152194302, content=<a href='/topic/show?id=f83866137f' target=_blank style='color:#2F92EE;'>#EHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6613, encryptionId=f83866137f, topicName=EHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937d11405368, createdName=qjddjq, createdTime=Thu Nov 07 04:24:00 CST 2019, time=2019-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=374825, encodeId=cdda3e482515, content=所以要调睡眠, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0225163045, createdName=146bea4cm28暂无昵称, createdTime=Tue Nov 05 19:24:18 CST 2019, time=2019-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=374823, encodeId=2c313e482321, content=可是焦虑就会睡不着,睡不好第二天会更焦虑 ,这不是恶性循环了吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLpFkye0MszfOIta2ICWOuagHxYneO5ibUMnoQ3chbt7QlevhbuytsickjZib2T6Rox9vCftFB4codXg/132, createdBy=8ab15083450, createdName=Korsean, createdTime=Tue Nov 05 17:32:57 CST 2019, time=2019-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050508, encodeId=f90b10505089e, content=焦虑是当年年轻人的共同问题,需要认真对待。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Tue Nov 05 16:24:00 CST 2019, time=2019-11-05, status=1, ipAttribution=)]
    2019-11-05 146bea4cm28暂无昵称

    所以要调睡眠

    0

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    2019-11-05 Korsean

    可是焦虑就会睡不着,睡不好第二天会更焦虑 ,这不是恶性循环了吗

    0

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    2019-11-05 明天jing

    焦虑是当年年轻人的共同问题,需要认真对待。

    0

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