Hypertension:CKD儿童血压控制是否有所改善

2018-01-07 国际循环编辑部 国际循环

对于慢性肾脏疾病(CKD)患者,高血压未控制是导致CKD进展和心血管疾病风险增加的主要因素之一。Hypertension发表的一项最新研究对儿童慢性肾脏疾病(CKiD)研究中两个时间段的血压控制情况进行对比分析。

对于慢性肾脏疾病(CKD)患者,高血压未控制是导致CKD进展和心血管疾病风险增加的主要因素之一。Hypertension发表的一项最新研究对儿童慢性肾脏疾病(CKiD)研究中两个时间段的血压控制情况进行对比分析。

研究者对CKiD研究中2005年1月1日~2008年7月1日(第一时间段)和2010年7月1日~2013年12月31日(第二时间段),两个时间段共计851例患者(其中第一及第二时间段患者数量分别为345例和506例)的随机血压及24小时动态血压监测数据进行比较。结果发现,校正年龄、性别、种族、社会经济因素、CKD持续时间、肾小球滤过率、蛋白尿、体重指数及降压药物应用等混杂因素后,两个时间段患者随机血压状态并无明显差异。高血压前期的患者比例均为15%,未控制的高血压患者比例分别为18%和17%(P=0.87)。对动态血压监测数据的分析显示,与第一时间段相比,第二时间段CKD患者的动态血压指数更高,隐匿性高血压患者数量更多(49% vs. 36%,P<0.001),平均睡眠血压指数及睡眠血压负荷均较高(P均<0.05)。

该研究提示,尽管与第一时间段相比,第二时间段期间高血压指南及有关CKD血压控制指南发表,但我们对于CKD儿童高血压的识别及治疗仍存在不足。此外,该研究也强调对于CKD患儿行常规动态血压监测的重要性。

原始出处:
Gina-Marie Barletta, et al. Is Blood Pressure Improving in Children With Chronic Kidney Disease? Hypertension. Jan 2018.

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    2018-09-24 feather89
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    2018-01-13 半夏微凉

    学习了谢谢分享

    0

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    2018-01-08 圣艮山

    学习了不少事情!!

    0

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    2018-01-08 flysky120

    学习一下知识了

    0

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    2018-01-07 hhh678

    henhao

    0

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