JAHA:植物蛋白对血脂的影响!

2017-12-20 xing.T MedSci原创

由此可见,采用植物蛋白替代动物蛋白降低了既定的脂质类型:低密度脂蛋白胆固醇、非高密度脂蛋白胆固醇和载脂蛋白B。需要更多高质量的随机试验来改善这一估计。

对于预防血管疾病方面,植物为基础的饮食具有广大的市场。虽然植物蛋白被认为是通过改变血脂来介导这种预防效应,但将植物蛋白特异性地替代动物蛋白后对血脂的影响尚不清楚。近日,心血管疾病领域权威杂志JAHA上发表了一篇荟萃分析文章,为了评估这种替代对可以降低心血管风险的既定脂质类型的影响,研究人员采用推荐评估、发展和评价系统对随机对照试验进行了系统评价和荟萃分析。

研究人员检索了MEDLINE、EMBASE和Cochrane登记中心,检索日期至2017年9月9日。研究人员纳入了植物蛋白替代动物蛋白≥3周后比较其对低密度脂蛋白胆固醇、非高密度脂蛋白胆固醇和载脂蛋白B影响的随机对照试验。两名评价者独立提取相关数据,并评估偏倚风险。数据通过采用一般的逆方差方法进行合并,以平均差异和95%可信区间进行表示。研究人员对异质性进行了评估(Cochran Q检验)和定量(I2统计),并采用推荐评估、发展和评价系统对证据的总体质量(确定性)进行评估。

该荟萃分析共有十二项随机对照试验符合纳入标准。植物蛋白替代动物蛋白后可使低密度脂蛋白胆固醇降低0.16 mmol/L(95%可信区间为-0.20至-0.12 mmol/L;P<0.00001;I2=55%;中等质量证据),非高密度脂蛋白胆固醇降低0.18 mmol/L(95%可信区间为-0.22至-0.14mmol/L;P<0.00001;I2=52%;中等质量证据),以及载脂蛋白B降低0.05g/L(95%可信区间为-0.06至-0.03g/L;P<0.00001;I2=30%;中等质量证据)。

由此可见,采用植物蛋白替代动物蛋白降低了既定的脂质类型:低密度脂蛋白胆固醇、非高密度脂蛋白胆固醇和载脂蛋白B。需要更多高质量的随机试验来改善这一估计。

原始出处:

Siying S. Li,et al. Effect of Plant Protein on Blood Lipids: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials.JAHA.2017. https://doi.org/10.1161/JAHA.117.006659

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    2018-07-08 xuyong535
  2. 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    2017-12-23 虈亣靌

    如此说来还是一个好事情

    0

  3. 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    2017-12-22 柳叶一刀
  4. 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    2017-12-22 大爰

    学习了谢谢分享!!

    0

  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Dec 21 03:49:07 CST 2017, time=2017-12-21, status=1, ipAttribution=)]
    2017-12-21 日月生辉

    学习了开始改变饮食习惯了

    0

  6. 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    2017-12-21 明月清辉

    谢谢分享.学习了

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Dec 21 03:49:07 CST 2017, time=2017-12-21, status=1, ipAttribution=)]
    2017-12-21 忠诚向上

    好好学习.天天向上

    0

  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Thu Dec 21 08:07:21 CST 2017, time=2017-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271111, encodeId=4ef92e111160, content=好好学习.天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Dec 21 07:54:07 CST 2017, time=2017-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271106, encodeId=9f402e110677, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Thu Dec 21 07:22:57 CST 2017, time=2017-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271067, encodeId=dde22e10675d, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 21 05:27:35 CST 2017, time=2017-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271059, encodeId=7bae2e1059a3, content=学习学习.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Dec 21 03:49:07 CST 2017, time=2017-12-21, status=1, ipAttribution=)]
    2017-12-21 榄枷檬

    谢谢分享

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1745269, encodeId=e4ee1e4526982, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Sun Jul 08 13:00:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271845, encodeId=1bd72e18451d, content=如此说来还是一个好事情, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Dec 21 03:49:07 CST 2017, time=2017-12-21, status=1, ipAttribution=)]
    2017-12-21 yjs木玉

    好好好好好好好好

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Dec 21 03:49:07 CST 2017, time=2017-12-21, status=1, ipAttribution=)]
    2017-12-21 1dd8c52fm63(暂无匿称)

    学习学习.继续关注

    0

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